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| ID | Type | Description | Link |
|---|---|---|---|
| 2017-A00917-46 | Other Identifier | ANSM |
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Based in an embodied approach of cognition, several studies have highlighted a direct link between perception of an object or an emotion and the associated motor responses. This study investigated in patients suffering from bipolar affective disorders whether the perception of emotional words involves an automatic sensorimotor simulation of approach and avoidance behaviors, and whether the perception of an object involves an automatic sensorimotor simulation of object prehension (affordance). We hypothesize that, in this pathology, low level (sensorimotor) cognitive processes are preserved whereas high-level (attentional) are altered. 20 patients suffering from bipolar affective disorders and 20 healthy controls will be recruited. The main objective is the emergence of sensorimotor compatibility effects in approach-avoidance task with emotional stimuli (gain between compatible vs incompatible conditions).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patients | Experimental | Patients suffering bipolar affective disorders and who will perform cognitive tasks + IQ + MINI + experimental task |
|
| control group | Active Comparator | Healthy volunteers (Control group) who will perform cognitive tasks + experimental task |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cognitive tasks + IQ + MINI | Behavioral | Patients will perform different tasks:
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| Measure | Description | Time Frame |
|---|---|---|
| response time for avoidance and affordance task | Comparison of response time for avoidance and affordance task between patients and healthy volunteers. | Months 24 |
| Measure | Description | Time Frame |
|---|---|---|
| response time for affordance task | Comparison of response time for affordance task between patients and healthy volunteers. | Months 24 |
| correlations with age at onset of the disease, the number of thymic decompensations and the existence of psychotic symptoms |
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Inclusion Criteria:
For patients:
For control group:
Exclusion Criteria:
For patients:
For control group:
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| Name | Affiliation | Role |
|---|---|---|
| Catherine MASSOUBRE, MD PhD | Centre Hospitalier Universitaire de Saint Etienne | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Chu Saint-Etienne | Saint-Etienne | 42055 | France |
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| ID | Term |
|---|---|
| D001714 | Bipolar Disorder |
| ID | Term |
|---|---|
| D000068105 | Bipolar and Related Disorders |
| D019964 | Mood Disorders |
| D001523 | Mental Disorders |
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| cognitive tasks | Behavioral | Healthy volunteers will perform only the cognitive tasks = reaction time alert TEA, Zimmermann and Fimm, 2005 + Edinburgh laterality questionnaire (Oldfield, 1971) + experimental task (approach/ avoidance and affordance task). |
|
These informations were collected of the medical file. |
| Months 24 |
| response time and cognitive tests | Correlation between response time and cognitive tests of patients and healthy volunteers. | Months 24 |