Study of Sensorimotor Compatibility Effects in Bipolar Affective Disorder.

Study of Sensorimotor Compatibility Effects in Bipolar Affective Disorder.

Based in an embodied approach of cognition, several studies have highlighted a direct link between perception of an object or an emotion and the associated motor responses. This study investigated in patients suffering from bipolar affective disorders whether the perception of emotional words involves an automatic sensorimotor simulation of approach and avoidance behaviors, and whether the perception of an object involves an automatic sensorimotor simulation of object prehension (affordance). We hypothesize that, in this pathology, low level (sensorimotor) cognitive processes are preserved whereas high-level (attentional) are altered. 20 patients suffering from bipolar affective disorders and 20 healthy controls will be recruited. The main objective is the emergence of sensorimotor compatibility effects in approach-avoidance task with emotional stimuli (gain between compatible vs incompatible conditions).

Inclusion Criteria:

For patients:

• Affiliated or entitled to a social security
• Aged between 18 and 55
• Patients of both sexes suffering from bipolar disorders (DSM V criteria) whatever the subtype
• Stabilized from a point of view clinical and therapeutic
• Euthymic (score <7 at the Hamilton scale, and score <8 at Young's scale)
• Must have given their informed consent before their participation in the study
• Be right-handed (score> 14 on the laterality scale)

For control group:

• Affiliated or entitled to a social security
• Must have given their informed consent before their participation in the study
• Be right-handed (score> 14 on the lateral scale)
• Aged 18 to 55 matched by age (± 5 years), sex, and on the study level of patients (years of schooling after primary school ± 2 years)

Exclusion Criteria:

For patients:

• Thymic acute decompensation
• Hamilton scale > 8, Young's scale > 9
• Montreal Cognitive Assessment (MOCA) <26
• History neurological pathology with cerebral impairment or serious somatic disease
• Disorders related to the use of a psychoactive substance, as defined by the DSM-V (abuse, dependence or withdrawal) within 6 months.
• IQ < 70
• History of head trauma

For control group:

• History of head trauma
• Neurological pathology with cerebral impairment or serious somatic disease
• Psychotropic treatment
• Disorders related to the use of a psychoactive substance, as defined by the DSM-V (abuse, dependence or withdrawal)
• IQ < 70