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| Name | Class |
|---|---|
| University of California, Berkeley | OTHER |
| Deakin University | OTHER |
| Chinese University of Hong Kong | OTHER |
| Hospital Authority, Hong Kong |
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Parkinson's disease (PD) is a common neurodegenerative disorder which is characterized by both motor and non-motor symptoms and usually affects people aged 50 years or above. Many studies showed eye movement deficits and visual changes in patients with PD.
Previous studies have also indicated that clinical eye movement training could enhance the functional performance of patients with various eye movement problems resulting from ocular and neurodegenerative diseases.
In this study, we will investigate the effectiveness of eye movement training on dynamic vision and functional performance in PD patients with oculomotor deficits.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control Group | Placebo Comparator | Receive 10 sessions of 45-minute (3 sessions per week) in-office leisure activities e.g. simple non-action computer games or board games (e.g. card and chess games) and 10-20 minutes of video watching at home |
|
| Intervention Group | Active Comparator | Receive 10 sessions of 45-minute office training (3 sessions per week) and 10-20 minute home training (3 sessions per week) of eye movement training |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Control Group | Other | Leisure activities |
| |
| Oculomotor Training Group |
| Measure | Description | Time Frame |
|---|---|---|
| Smooth Vergence eye movements | Smooth vergence eye movement is measured using a head-mounted eye tracking while fixating at an approaching target moving at different speeds | Change from baseline at week 4 and change from baseline at week 12 |
| Measure | Description | Time Frame |
|---|---|---|
| Oculomotor characteristics | With the use of eye tracking device, eye movement behavior of participants can be measured and analysed while performing the following tasks.
|
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Inclusion Criteria:
Parkinson's Disease diagnosed by a neurologist or geriatrician with the range of Stage
1 to 4 (Hoehn and Yahr Classification)
Able to speak and comprehend Cantonese dialect
Able to travel independently
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Allen Ming Yan Cheong, PhD | The Hong Kong Polytechnic University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Allen MY Cheong | Hong Kong | Hong Kong |
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| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| ID | Term |
|---|---|
| D035061 | Control Groups |
| ID | Term |
|---|---|
| D015340 | Epidemiologic Research Design |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D012107 | Research Design |
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| OTHER_GOV |
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| Other |
Eye movement training |
|
| Change from baseline at week 4 and change from baseline at week 12 |
| Sentence reading performance | To evaluate the effectiveness of the interventions on sentence reading using MNREAD charts in Chinese. These charts developed in our laboratory are used to measure the effectiveness of sentence reading in terms of reading speed and critical print size. | Change from baseline at week 4 and change from baseline at week 12 |
| Passage reading performance | To evaluate the effectiveness of the interventions on passage reading using International Reading speed Test (IReST). IReST is used to evaluate the effectiveness of passage reading performance by measuring the reading speed. | Change from baseline at week 4 and change from baseline at week 12 |
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
| D008722 | Methods |