Somesthesic Role of the Ventro-lateral Prefrontal Cortex in Speech Motor Learning fMRI Study
Somesthesic Role of the Ventro-lateral Prefrontal Cortex in Speech Motor Learning fMRI Study
These studies test the hypothesis that frontal areas of the brain participate in the cortical networks involved in the somotosensory processing that happens during speech motor learning.
This work aims to study the role of sensory systems in human motor learning and specifically addresses the involvement of somatosensory cortical networks in motor learning of speech. Previous studies in the literature have highlighted the plasticity of cortical sensory networks, notably the primary and secondary somatosensory cortex and the ventral premotor cortex, during motor learning tasks. The present project focuses on the somatosensory region with connections to the sensorimotor regions of the frontal and parietal cortex. We propose to use neuroimaging (fMRI), in order to verify which areas in the prefrontal cortex are part of the sensorimotor network used in the learning of speech motor tasks in humans. Subjects will be tested in the fMRI scanner while performing either a behavioral task in which the auditory feedback of their own speech is altered or while performing a vibrotactile discrimination task.
Inclusion Criteria:
Exclusion Criteria:
Left-handed subjects
Criteria for contraindications to protocol fMRI scans
Existence of a severe general condition: cardiac, respiratory, hematological, renal, hepatic, cancerous.
Hearing, language (including dyslexia), neurological or psychiatric disorders.
Participation in other ongoing intervention research protocols with exclusionary period or within the previous week
Drug treatment likely to modulate brain activity: benzodiazepines, antidepressants, neuroleptics, lithium, etc.
Protected persons referred to in articles L1121 5 to L1121 8 of the French CSP: