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| Name | Class |
|---|---|
| The Rutgers Asian Resource Center for Minority Aging Research (RCMAR) | UNKNOWN |
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The rapid growth rate and unique challenges as a new immigrant group call for a better understanding of the social and health needs of the older Asian Americans (AAs) population. Overwhelming numbers of AAs, a fast-growing first-generation immigrant group, suffer from type 2 diabetes (T2D) and its consequences of poorly controlled blood glucose. For the older AAs, there are higher prevalence rates, worse diabetes control, and higher rates of complications due to limited English proficiency and health literacy. Despite the evidence concerning the effects of dietary interventions on glycemic control by well-controlled feeding studies in mainstream Americans, a lack of clinical trials of culturally tailored interventions often imposes serious barriers to translate and implement such fruitful and innovative approaches in individuals from ethnic minority communities such as AAs.
The proposed study will use a randomized, controlled design with a sample of 60 AAs aged 65 years or older. Metabolomics methodologies will be incorporated into this research to provide a global picture of metabolites' responses to personalized behavioral nutrition (PBN) intervention. The study results will obtain the necessary information to conduct a meaningful community-based clinical trial to test the effectiveness of PBN in improving dietary patterns and glycemic control in older AAs.
This study is designed with two aims:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control group | Active Comparator | This group will receive 4-week diabetes nutrition education with digital self-monitoring for diet and blood glucose. |
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| Intervention group | Experimental | This group will receive 4-week personalized behavioral nutrition intervention with digital self-monitoring for diet and blood glucose and diabetes nutrition education. Participants will discuss the personalized nutrition change goals and recommendations based on metabolic profiling for assessing dietary patterns. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ADA-based nutrition education with digital self-monitoring | Behavioral | Diabetes nutrition education developed by the American Diabetes Association with digital self-monitoring for diet and physical activity |
| Measure | Description | Time Frame |
|---|---|---|
| Glycemic control | Change in Glycemic control as assessed by HbA1C levels | Baseline, 4-week, 8-week |
| Measure | Description | Time Frame |
|---|---|---|
| Metabolites profiles | Change in 302 targeted metabolites profiles (e.g. Aconitic acid, Citric acid, Glycolic acid, Homovanillic acid, 2-ET-3-OH-Propionate, 3-OH-Isobutyrate, 3-OH-Isovalerate, 2-3-OH-Propionate, and Uracil) | Baseline, 4-week |
| Lipids profiles |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jisook Ko, PhD | The University of Texas Health Science Center at San Antonio | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| The University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34160184 | Derived | Ko J, Wang J, Du Y, Jiwani R, Li C. Personalized Behavioral Nutrition Among Older Asian Americans: Study Protocol. Nurs Res. 2021 Jul-Aug 01;70(4):317-322. doi: 10.1097/NNR.0000000000000514. |
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| ID | Term |
|---|---|
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
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| Personalized Behavioral Nutrition (PBN) intervention group | Behavioral | Personalized behavioral nutrition intervention consisting of digital self-monitoring for diet and physical activity, personalized nutrition change goal and recommendation, and diabetes nutrition education developed by ADA |
|
Change in lipids profiles (LDL, HDL, total cholesterol, triglycerides) as assessed by serum lipids profiling |
| Baseline, 4-week, 8-week |
| Weight | Change in weight as assessed by the Withings electronic scale | Baseline, 4-week, 8-week |
| Dietary intake | Daily dietary intake as measured by the Fitbit food log | Over the 4-week |
| Physical activity | Daily steps taken as measured by the Fitbit wristband | Over the 4-week |
| In-home self-monitoring of blood glucose | Daily blood glucose level as measured by wireless glucometer | Over the 4-week |
| D004700 | Endocrine System Diseases |