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lack of funding
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| Name | Class |
|---|---|
| Shanghai Children's Medical Center | OTHER |
| Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | OTHER |
| Obstetrics & Gynecology Hospital of Fudan University | OTHER |
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A multicenter interventional study using evidence-based collaborative quality improvement to reduce mortality and major morbidities of very preterm infants in six neonatal centers in Shanghai
A multicenter interventional study using evidence-based collaborative quality improvement to reduce mortality and major morbidities of very preterm infants using evidence-based collaborative quality improvement interventions including benchmarking, potential better practice list, PDSA implementation and collaborative learning.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention period | Experimental | The 1.5-year period during which all six participating centers receive evidence-based collaborative quality improvement interventions including benchmarking, potential better practice list, PDSA implementation, and collaborative learning |
|
| Baseline period | No Intervention | The 2-year period before the collaborative quality improvement intervention |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Evidence-based collaborative quality improvement | Behavioral | Evidence-based collaborative quality improvement interventions including benchmarking, potential better practice list, PDSA implementation and collaborative learning |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality or any major morbidity | It is a binary varibale (1/0). The variabel would be setted into "1",if death or with any of the following major morbidities: bronchopulmonary dysplasia, necrotizing stage II or above, retinopathy of prematurity stage III or above, intraventricular hemorrhage grade III or above or cystic periventricular leukomalacia and late-onset epsis | During first NICU hospitalization (about 1-4 months) |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | It is a binary varibale (1/0). The variabel would be setted into "1",if patients dead during hospitalization or 28 days after discharge against medical advice | During the procedure (about 1-4 months) |
| Bronchopulmonary dysplasia |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Obstetrics and Gynecoloy Hospital of Fudan University | Shanghai | Shanghai Municipality | 200011 | China | ||
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25946279 | Background | Rysavy MA, Li L, Bell EF, Das A, Hintz SR, Stoll BJ, Vohr BR, Carlo WA, Shankaran S, Walsh MC, Tyson JE, Cotten CM, Smith PB, Murray JC, Colaizy TT, Brumbaugh JE, Higgins RD; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Between-hospital variation in treatment and outcomes in extremely preterm infants. N Engl J Med. 2015 May 7;372(19):1801-11. doi: 10.1056/NEJMoa1410689. | |
| 28232518 |
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| Shanghai First Maternity and Infant Hospital |
| OTHER |
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It is a binary varibale (1/0). The variabel would be setted into "1",if patients reveived respiratory support or oxygen at 36 weeks' corrected gestational age or on discharge
| During first NICU hospitalization (about 1-4 months) |
| Necrotizing enterocolitis | It is a binary varibale (1/0). The variabel would be setted into "1",if patients appeared with NEC stage II or above | During first NICU hospitalization (about 1-4 months) |
| Severe brain injury | It is a binary varibale (1/0). The variabel would be setted into "1",if patients appeared with intraventricular hemorrhage grade III or above within 28 days after birth or cystic periventricular leukomalacia | During first NICU hospitalization (about 1-4 months) |
| Retinopathy of prematurity | It is a binary varibale (1/0). The variabel would be setted into "1",if patients appeared with ROP stage III or above. | During first NICU hospitalization (about 1-4 months) |
| Late-onset sepsis | It is a binary varibale (1/0). The variabel would be setted into "1",if patients appeared with culture-proven sepsis after 72 hours after birth | During first NICU hospitalization (about 1-4 months) |
| Length of NICU stay | days for the first NICU hospitalization | During first NICU hospitalization (about 1-4 months) |
| Children's Hospital of Shanghai Jiao Tong University |
| Shanghai |
| Shanghai Municipality |
| 200062 |
| China |
| Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine | Shanghai | Shanghai Municipality | 200092 | China |
| Shanghai First Maternity and Infant Hosipital | Shanghai | Shanghai Municipality | 200126 | China |
| Shanghai Children's Medical Center | Shanghai | Shanghai Municipality | 200127 | China |
| Children's Hospital of Fudan University | Shanghai | Shanghai Municipality | 201102 | China |
| Background |
| Smith LK, Blondel B, Van Reempts P, Draper ES, Manktelow BN, Barros H, Cuttini M, Zeitlin J; EPICE Research Group. Variability in the management and outcomes of extremely preterm births across five European countries: a population-based cohort study. Arch Dis Child Fetal Neonatal Ed. 2017 Sep;102(5):F400-F408. doi: 10.1136/archdischild-2016-312100. Epub 2017 Feb 23. |
| 31167207 | Background | Soll RF, McGuire W. Evidence-Based Practice: Improving the Quality of Perinatal Care. Neonatology. 2019;116(3):193-198. doi: 10.1159/000496214. Epub 2019 Jun 5. |
| 27381936 | Background | Zeitlin J, Manktelow BN, Piedvache A, Cuttini M, Boyle E, van Heijst A, Gadzinowski J, Van Reempts P, Huusom L, Weber T, Schmidt S, Barros H, Dillalo D, Toome L, Norman M, Blondel B, Bonet M, Draper ES, Maier RF; EPICE Research Group. Use of evidence based practices to improve survival without severe morbidity for very preterm infants: results from the EPICE population based cohort. BMJ. 2016 Jul 5;354:i2976. doi: 10.1136/bmj.i2976. |
| 29370845 | Background | Zaka N, Alexander EC, Manikam L, Norman ICF, Akhbari M, Moxon S, Ram PK, Murphy G, English M, Niermeyer S, Pearson L. Quality improvement initiatives for hospitalised small and sick newborns in low- and middle-income countries: a systematic review. Implement Sci. 2018 Jan 25;13(1):20. doi: 10.1186/s13012-018-0712-2. |
| 24041863 | Background | Zhou Q, Lee SK, Jiang SY, Chen C, Kamaluddeen M, Hu XJ, Wang CQ, Cao Y. Efficacy of an infection control program in reducing ventilator-associated pneumonia in a Chinese neonatal intensive care unit. Am J Infect Control. 2013 Nov;41(11):1059-64. doi: 10.1016/j.ajic.2013.06.007. Epub 2013 Sep 14. |
| 31988152 | Background | Lee SK, Beltempo M, McMillan DD, Seshia M, Singhal N, Dow K, Aziz K, Piedboeuf B, Shah PS; Evidence-based Practice for Improving Quality Investigators. Outcomes and care practices for preterm infants born at less than 33 weeks' gestation: a quality-improvement study. CMAJ. 2020 Jan 27;192(4):E81-E91. doi: 10.1503/cmaj.190940. |