Ultrasound Quantification of Liver Fat

Ultrasound Quantification of Liver Fat

The investigators plan a prospective study designed to evaluate the accuracy of a new ultrasound method for quantification of liver fat content.

MRI proton density fat fraction (PDFF) will serve as the reference standard for liver fat fraction measurements. The strength of agreement between ultrasound derived fat fraction (UDFF) and PDFF will be the outcome of interest for this study.

Inclusion Criteria:

• Patients 16 years of age or older with known fatty liver disease (based upon prior MRI or ultrasound), or at risk for fatty liver disease (obese).

Exclusion Criteria:

• Subject under the age of 16
• Pregnant subject
• Subjects who cannot cooperate with performance of the ultrasound exam
• Subjects who cannot cooperate with performance of the MRI exam
• Subjects who have contraindications to MRI
• Subjects who might require sedation or anesthesia to undergo study imaging