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There is an urgent need for transcatheter tricuspid interventions, as pharmaceutical therapy becomes ineffective in advanced disease stages and surgery remains associated with high mortality rates. Despite the promising results, in some patients, although good procedural results were achieved, no clinical improvements were measured. Right ventricular dysfunction is suspected to be the cause of the failed therapeutic strategy. Therefore this study aims to analyze right ventricular function with magnet resonance imaging before and 3-months after the procedure in order to gain insight into the prevalence and dynamics of right ventricular dysfunction in severe tricuspid regurgitation and to identify possible predictors for treatment failure.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| MR-TTE | Other | Patient receiving cardiac magnet resonance imaging and echocardiography |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Magnet resonance imaging | Diagnostic Test | Patients will receive a cardiac magnet resonance tomography before and 3-month after the procedure |
|
| Measure | Description | Time Frame |
|---|---|---|
| Influence of transcatheter tricuspid intervention on tricuspid annular plane systolic excursion resonance tomography and echocardiography | Changes on tricuspid annular plane systolic excursion in magnet resonance tomography and echocardiography after of transcatheter tricuspid intervention | 3 month |
| Influence of transcatheter tricuspid intervention on right ventricular basal diameter excursion in resonance tomography and echocardiography | Changes on right ventricular basal diameter in resonance tomography and echocardiography after transcatheter tricuspid intervention | 3 Month |
| Influence of transcatheter tricuspid intervention on right ventricular stroke volume resonance tomography and echocardiography | Changes on right ventricular stroke volume in resonance tomography and echocardiography after transcatheter tricuspid intervention | 3 Month |
| Influence of transcatheter tricuspid intervention on right ventricular ejection fraction resonance tomography and echocardiography | Changes on right ventricular ejection fraction in resonance tomography and echocardiography after transcatheter tricuspid intervention | 3 Month |
| Influence of transcatheter tricuspid intervention on right ventricular global longitudinal strain resonance tomography and echocardiography | Changes on right ventricular global longitudinal in resonance tomography and echocardiography after transcatheter tricuspid intervention | 3 Month |
| Influence of transcatheter tricuspid intervention on right ventricular fractional area change resonance tomography and echocardiography |
| Measure | Description | Time Frame |
|---|---|---|
| Exercise Testing with 6 min walking test | Changes on walked distance after transcatheter tricuspid intervention | 3 month |
| rehospitalization rate | Detection of rehospitalization rate after transcatheter tricuspid intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Muhammed Gercek, Dr. med. | Assistant physician | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Herz- und Diabeteszentrum, NRW | Bad Oeynhausen | North Rhine-Westphalia | 32545 | Germany |
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| ID | Term |
|---|---|
| D014262 | Tricuspid Valve Insufficiency |
| ID | Term |
|---|---|
| D006349 | Heart Valve Diseases |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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Changes on right ventricular fractional area change in resonance tomography and echocardiography after transcatheter tricuspid intervention |
| 3 Month |
| Influence of transcatheter tricuspid intervention on tricuspid regurgitant fraction resonance tomography and echocardiography | Changes on tricuspid regurgitant fraction in resonance tomography and echocardiography after transcatheter tricuspid intervention | 3 Month |
| 3 month |
| Stroke | Detection of stroke rate after transcatheter tricuspid intervention | 3 month |
| Death due to cardiovascular complication | Detection of death rate due to cardiovascular complications after transcatheter tricuspid intervention | 3 month |
| Influence of transcatheter tricuspid intervention on the cardiopulmonary exercise capacity | Changes on aerobic capacity and endurance using the cardiopulmonary exercise testing (vO2max in milliliter per minute per kilogram) | 3 month |