Relationship Between Pre-induction Electroencephalogram Pattern of Adult Patients and Their Sensitivity to Propofol

Relationship Between Pre-induction Electroencephalogram Pattern of Adult Patients and Their Sensitivity to Propofol

The induction dose of propofol is generally determined based on patients' characteristics, underlying disease, general condition, and also by clinician's experiences. However, It is difficult to anticipate and objectively calculate an adequate dose of propofol for every patient considering the variability of an individual's response to propofol. If there is a specific pattern in EEG prior to induction of anesthesia that can provide information about the patient's susceptibility to propofol, every induction may be performed far more smoothly with a precisely optimized dose of propofol for each patient. The study is to find a relationship between the pre-induction EEG pattern of adult patients and their sensitivity to propofol.

Inclusion Criteria:

• Adult patients undergoing general anesthesia

Exclusion Criteria:

• Patients undergoing cardiac or brain surgery
• Patients with neurological deficit or impaired communication (Glasgow Coma Scale < 15)
• Unstable vital sign (cardiogenic, hemorrhagic, septic shock)
• Patients with eclampsia
• Patients who administered preoperative anxiolytics
• Patients who do not require intubation
• Patients who are considered unsuitable for the study