Mesotherapy Versus Systemic Therapy in Treating Neck Pain Related to Herniated Disc

Intradermal Mesotherapy Versus Systemic Therapy in Treating Neck Pain to Cervical Disc Herniation: A Prospective Randomized Study

Introduction: Neck pain is a global public health concern, that ranked 4th highest health condition in terms of disability as measured by years lived with disability. The aim of this study is to compare the efficiency of one-session mesotherapy application with systemic therapy in treating neck pain related to cervical disk herniation.

Methods: This is a prospective parallel randomized controlled trial conducted with patients admitted to our emergency department with neck pain related to cervical disc herniation. A mixture of thiocolchicoside, lidocaine and tenoxicamwas administered via mesotherapy in one group, and intravenous administration of dexketoprofen was applied to the other group. We compared the changes in pain intensity at 60thminute, 120thminute and 24th hours after treatment using Visual Analogue Scale (VAS),and adverse effects of the treatment methods among the study groups.

Inclusion Criteria:

• 18 years and older age
• Admission to Emergency Department (ED) with acute cervical pain related to cervical disk herniation.

Exclusion Criteria:

• Taking analgesic drugs before admission
• Having VAS score of lower than 4 on admission
• Having diabetes mellitus
• Body mass index>30 kg/m2
• Pregnancy
• Lactation
• Having active bleeding or bleeding disorder
• Having active or recurrent gastrointestinal hemorrhage or ulcer, or history of these conditions
• Having a serious or life-threatening condition (stroke, intracranial hemorrhage, heart attack, cardiac tamponade, pneumothorax, hemothorax, flail chest, etc.).