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The study investigates the effects of induced pneumoperitoneum during surgery on ventilatory parameters including peak inspiratory pressure, lung compliance, end-tidal CO2 at specific time-points: after induction of anaesthesia, after induction of surgery, one-hour and two-hours during surgery, end of surgery.
The effects of pneumoperitoneum are compared between two groups of patients: patients undergoing laparoscopic surgery and patients undergoing robotic-assisted surgery. No intervention was performed in this study and the decision for type of surgery performed was made by the attending surgeon prior to study inclusion
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Video-assisted surgery | Patients undergoing video-assisted major abdominal surgery (VAS) in Trendelenburg position. The decision regarding the type of VAS was made by the attending surgeon prior to study inclusion. Twenty-five consecutive patients undergoing classic laparoscopic surgery and twenty-five patients undergoing robotic-assisted surgery will be included in the study. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| mechanical ventilation during video-assisted surgery | Procedure | observed variation of ventilatory parameters during video-assisted surgery |
|
| Measure | Description | Time Frame |
|---|---|---|
| lung compliance | change in lung compliance (mL/cmH2O) before and after induction of pneumoperitoneum in patients undergoing VAS. Lung compliance is automatically calculated by the anesthesia machine during surgery. The study compares the magnitude in change associated with VAS. | one-hour and two-hours after induction of pneumoperitoneum |
| Measure | Description | Time Frame |
|---|---|---|
| arterial to end-tidal CO2 difference | difference in arterial to end-tidal CO2 (mmHg) during surgery. Arterial blood samples and end-tidal CO2 were simultanously obtained at the specific time-points. | one-hour and two-hours after induction of pneumoperitoneum |
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Inclusion Criteria:
Exclusion Criteria:
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consecutive patients undergoing video-assisted surgery in a university hospital after inclusion and exclusion criteria have been met. Video-assisted surgery is defined by either classic laparoscopic surgery or robotic assisted surgery and the medical decision between the two types of surgery was performed by the attending surgeon prior to patient inclusion (unrelated to the study).
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| Name | Affiliation | Role |
|---|---|---|
| Dana Tomescu, Prof | Fundeni Clinical Institute | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fundeni Clinical Institute | Bucharest | 022328 | Romania |
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