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Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome). In obese patients undergoing laparoscopic bariatric surgeries, the risk of postoperative pulmonary complications (PPCs) increases significantly with general anesthesia. Previous studies have shown that protective lung ventilation strategies could improve intraoperative oxygenation and lung mechanics.
In this study would compare the effect of optimum individualized high PEEP versus standard PEEP - on postoperative pulmonary complications
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| titrate PEEP | Experimental | individulaized PEEP starting 7cmH2O titrated to best static compliance (Cstat) ranging from 50 -100 cmH2O |
|
| standard | Active Comparator | standard PEEP of 5 cmH2O |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| titated PEEP to best static compliance | Other | the Intraoperative PEEP will be titrated to best static compliance for each patient |
|
| Measure | Description | Time Frame |
|---|---|---|
| postoperative pulmonary complication | pneumonia-atelactasis-bronchospasm-respiratory failure | postoperative 10 days after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Pulmonary functions test | This test includes these values :FVC (forced vital capacity ) FEV1( forced expiratory volume in one sec ) FEV1% and FVC% | postoperative 1st , 3rd and 5th day |
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Inclusion Criteria:
Patients were eligible for participation if the met the following criteria
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| wessam selima, MD | Contact | +201001958858 | w.z.selima@med.asu.edu.eg | |
| ghada sharafeldin, MSc | Contact | +201159296642 | ghadasharaf.92@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ain shams university | Recruiting | Cairo | Cairo Governorate | Egypt |
the results
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| ID | Term |
|---|---|
| D053120 | Respiratory Aspiration |
| ID | Term |
|---|---|
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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