A Study to Evaluate the Efficacy and Safety of ALH-L1005 in Patients With Chronic Periodontitis

A Multi-center, Randomized, Double-Blind, Phase II Clinical Trial to Evaluate the Efficacy and Safety of 12-week Treatment of ALH-L1005 600 mg or 1200 mg in Patients With Chronic Periodontitis

The main objective of this study is to evaluate efficacy and safety of ALH-L1005 in patients with chronic periodontitis

Inclusion Criteria:

• Men or women ages 18 and over, under 79 years of age
• Patients diagnosed with chronic periodontitis
• Patients with 4 teeth and over whose pocket depth is ≥ 4 mm and clinical attachment level is ≥ 3 mm
• Patients who are voluntarily participated in clinical trial

Exclusion Criteria:

• History of antibiotic therapy within the 1 month prior to study
• Those who had undergone any dental surgical or non-surgical therapy within 3 months prior to the start of the study
• Subjects who are pregnant/ lactating
• Smokers
• Patients who take Anticoagulants or Antiplatelet Agents
• With Systemic diseases that affect periodontal conditions such as: diabetes, hypertension and diseases of immune system