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To assess whether orange peel fermentation has the effect of reducing body fat in adults
This is a double-blind and randomized study. Subjects are informed to consume the samples every day for 2 months. The clinical diagnosis item of overweight or fatty liver is evaluated by the doctor. The questionnaires are collected at every visit of the trial.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Placebo | Placebo Comparator | consume 1 sachet per day for 2 months |
|
| orange peel fermentation | Experimental | consume 1 sachet per day for 2 months |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Placebo | Dietary Supplement | consume 1 sachet per day for 2 months |
| |
| Measure | Description | Time Frame |
|---|---|---|
| The change of body fat mass | The body fat mass (kg) was assessed by InBody770 | Weeks 0, 4 and 8 |
| The change of Triglyceride | Venous blood was sampled to measure concentrations of Triglyceride | Weeks 0, 4 and 8 |
| The change of Total cholestrol | Venous blood was sampled to measure concentrations of Total cholestrol | Weeks 0, 4 and 8 |
| The change of HDL-cholestrol | Venous blood was sampled to measure concentrations of HDL-cholestrol | Weeks 0, 4 and 8 |
| The change of LDL-cholestrol | Venous blood was sampled to measure concentrations of LDL-cholestrol | Weeks 0, 4 and 8 |
| The change of body mass index (BMI) | BMI is a measurement of a person's leanness or corpulence based on their height and weight, and is intended to quantify tissue mass.The body mass index (BMI, kg/m^2) and body mass (kg) were assessed by InBody770. | Weeks 0, 4 and 8 |
| The change of body fat percentage | The body fat percentage (%) was assessed by InBody770. | Weeks 0, 4 and 8 |
| The change of visceral fat |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| HUANG YU-JYUN | Contact | 0934173838 | nneder34@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| LIOU JYH-MING, Doctor | National Taiwan University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Taiwan University Hospital | Recruiting | Taipei | Taiwan | 114 | Taiwan |
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| ID | Term |
|---|---|
| D050177 | Overweight |
| D065626 | Non-alcoholic Fatty Liver Disease |
| ID | Term |
|---|---|
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
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| ID | Term |
|---|---|
| C031172 | 4-META resin |
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| orange peel fermentation |
| Dietary Supplement |
consume 1 sachet per day for 2 months |
|
|
The visceral fat (10 cm^2) was assessed by InBody770.
| Weeks 0, 4 and 8 |
| The change of fasting glycemia | Venous blood was sampled to measure concentrations of fasting glycemia | Weeks 0, 4 and 8 |
| The change of aspartate aminotransferase | Venous blood was sampled to measure concentrations of aspartate aminotransferase | Weeks 0, 4 and 8 |
| The change of alanine aminotransferase | Venous blood was sampled to measure concentrations of alanine aminotransferase | Weeks 0, 4 and 8 |
| The change of albumin | Venous blood was sampled to measure concentrations of creatine | Weeks 0, 4 and 8 |
| The change of creatine | Venous blood was sampled to measure concentrations of creatine | Weeks 0, 4 and 8 |
| The change of uric acid | Venous blood was sampled to measure concentrations of uric acid | Weeks 0, 4 and 8 |
| The change of white blood cell | Venous blood was sampled to measure concentrations of white blood cell | Weeks 0, 4 and 8 |
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D005234 | Fatty Liver |
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |