Effect of Intake of Citron(Citrus Junos Siebold ex Tanaka) Peel Extract on Blood Cholesterol.

A 12-week, Randomized, Double-blind, Placebo-controlled Human Trial to Evaluate the Efficacy and Safety of Citron(Citrus Junos Siebold ex Tanaka) Peel Extract on Improvement of Blood Cholesterol

This study was conducted to investigate the effects of daily supplementation of Citron(Citrus Junos Siebold ex Tanaka) Peel Extract on improvement of Blood Cholesterol.

This study was a 12 weeks, randomized, double-blind, placebo-controlled human trial. Twenty subjects were randomly divided into Citron(Citrus Junos Siebold ex Tanaka) Peel Extract or a placebo group. Blood cholesterol profiles before and after the intervention.

Inclusion Criteria:

• Age 19-75 years with Total cholesterol 200-239 mg/dL

Exclusion Criteria:

• Lipid lowering agent within past 6 months
• Severe cardiovascular disease(Mvodardial infarction, stroke, etc)
• Renal disease(Heredity hyperlipidemia, Acute/Chronic renal failure, Nephrotic syndrome, ect)
• Cancer, Respiratory organ disease(Asthma, Chronic obstructive pulmonary disease)
• Diabetes mellitus
• Allergic or hypersensitive to any of the ingredients in the test products
• History of disease that could interfere with the test products or impede their absorption
• Under antipsychotic drugs therapy within past 2 months
• History of alcohol or substance abuse
• Participation in any other clinical trials within past 2 months
• Laboratory test by show the following results
• Pregnancy or breast feeding
• Not Contraception(except: Surgery for female infertility)