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In this prospective, unicentric, case-control study, the main aim is to analyze joint movement and walking patterns in patients with acute stroke with a marker-free motion capture system. Case group: Stroke patients who fulfill the inclusion criteria are invited to participate in the study during admission. The evaluation consists of a workout designed by expert rehabilitation physicians and neurologists that is performed by the patient in front of the Microsoft Kinect camera. The custom-built software Akira record the joint angles of body trunk and upper limbs during the workout. The kinematic data will be analyzed with a machine learning algorithm that classifies the participant according to the kinematic data in normal movement or impaired movement (with the degree of impairment) by age decade. Control group: healthy participants (without neurological or osteomuscular diseases) matched by age and sex with cases 1:1. The correlation between kinematic and clinical scales (NIHSS) and functional scales (modified Rankin Scale) will be analyzed. A secondary objective will be to analyze the predictive value of the kinematic measurements with the functional outcome at three months
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cases | Acute stroke patients during the first week of evolution |
| |
| Control | Age and sex 1:1 healthy participants |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Kinematic metrics | Other | kinematic metrics recorded with Kinect (register brand) and extracted with Akira (register brand) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Kinematic metrics: join angles | The kinect camera together with the software Akira will be used to automatically measure the degree angle of the following body joints: shoulder in abduction, shoulder inflexion, elbow in extension and in flexion and the angle formed by the forearm and the trunk with the shoulder in abduction. | The change between the first week of index stroke (acute phase) and at 3 months after index stroke |
| Kinematic metrics: movement acceleration | The kinect camera together with the software Akira will be used to automatically measure the acceleration of the following movements: shoulder abduction and shoulder flexion. | The change between the first week of index stroke (acute phase) and at 3 months after index stroke |
| Kinematic metrics: movement pattern | The kinect camera together with the software Akira will be used to automatically measure the pattern of the following movements: trunk oscillation during standing position and during walking; and trunk oscillation during seating position with opened and closed eyes. | The change between the first week of index stroke (acute phase) and at 3 months after index stroke |
| Measure | Description | Time Frame |
|---|---|---|
| Relationship of kinematic measures with the degree of disability after stroke. | Correlation between the kinematic metrics described before (joint angles, movement acceleration and movement pattern) and the degree of disability, measured y the modified Rankin scale. The modified Rankin Scale (mRS) is a extensively use scale to measure dependency after stroke. The minimum value is 0 (no sequels or disability) and the maximum value is 6 (dead). The lower the score in the scale, the better is the outcome. |
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Inclusion Criteria:
Exclusion Criteria:
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Acute stroke patients and healthy controls, matched by age and sex. The inclusion and exclusion criteria are defined below
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| María Alonso de Leciñana, MD PhD | Contact | +34 917 277 444 | malecinanacases@salud.madrid.org | |
| Raquel Gutiérrez Zúñiga, MD | Contact | +34 917 277 444 | rgutierrezz@salud.madrid.org |
| Name | Affiliation | Role |
|---|---|---|
| María Alonso de Leciñana, MD PhD | Hospital Universitario La Paz, IdiPAZ | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| La Paz University Hospital, IdiPAZ | Recruiting | Madrid | 28046 | Spain |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| At 3 months after the index stroke |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |