Testing the Noradrenergic Hypothesis of Transcutaneous Vagus Nerve Stimulation

Testing the Noradrenergic Hypothesis of Transcutaneous Vagus Nerve Stimulation

This study investigates the capacity of non-invasive vagus nerve stimulation, applied at the ear, to alter to measures of locus coeruleus output pupil diameter and EEG alpha power. Non-invasive alteration in locus coeruleus output is of interest in regard to basic science and has potential clinical implications in a number of conditions.

Inclusion Criteria:

• Healthy, 18 years of age or older.

Exclusion Criteria:

• self-report of mood disorders, prescription and non-prescription drug use which includes stimulants including caffeine and nicotine