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| Name | Class |
|---|---|
| Belarusian Medical Academy of Post-Graduate Education | OTHER |
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Treatment of chronic medium-severe periodontitis with mesenchymal stem cells and mesenchymal stem cells predifferentiated in osteogenic direction
The bone defect will be filled with a porous membrane based on bone collagen measuring 5x5 mm or more with mesenchymal stem cells and mesenchymal stem cells predifferentiated in osteogenic direction
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| mesenchymal stem cells | Experimental | standard treatment according to clinical protocols plus mesenchymal stem cells |
|
| standard treatment | Active Comparator | standard treatment according to clinical protocols |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| mesenchymal stem cells | Biological | autologous mesenchymal stem cells |
| |
| Measure | Description | Time Frame |
|---|---|---|
| number of patients cured | number of patients cured | 1 month |
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Inclusion Criteria:
- chronic medium-severe periodontitis
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Igor Volotovski, Prof | Head of the Lab of Institute of Biophysics and Cell Engineering | Study Director |
| Sergey Rubnikovich, Prof | Head of the Department of Prosthodontics of BMAPE | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | Minsk | 220072 | Belarus |
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| standard treatment |
| Other |
standard treatment according to clinical protocols |
|
| ID | Term |
|---|---|
| D055113 | Chronic Periodontitis |
| D010518 | Periodontitis |
| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D002908 | Chronic Disease |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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