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It has recently been suggested that cocoa may improve exercise performance and recovery. This study aim to evaluate the plasma and fecal metabolome after 10 weeks of cocoa supplementation during the training period in recreational athletes to detect possible metabolites involved in the observed benefits of cocoa in athletes
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cocoa group | Experimental | 5 g/day of flavonoid-rich defatted cocoa for 10 weeks |
|
| Placebo group | Placebo Comparator | 5 g/day of maltodextrin for 10 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| cocoa | Dietary Supplement | Sachets of 5 grams of cocoa daily supplementation |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Fecal microbiota | Abundance of bacterial taxa determined by 16SRNAr gene sequencing | Changes from baseline to 10 weeks of intervention |
| Fecal metabolome profile | Abundance of fecal metabolites, metabolic networks, and metabolic pathways determined by High Pressure Liquid Chromatography-Mass Spectrometry | Changes from baseline to 10 weeks of intervention |
| Plasma metabolome profile | Abundance of blood metabolites, metabolic networks, and metabolic pathways activity determined by High Pressure Liquid Chromatography-Mass Spectrometry | Changes from baseline to 10 weeks of intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Mar Larrosa, PhD | Universidad Europea de Madrid | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universidad Europea de Madrid | Villaviciosa de Odón | Madrid | 28670 | Spain |
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| ID | Term |
|---|---|
| D000069956 | Chocolate |
| ID | Term |
|---|---|
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |
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| Placebo |
| Dietary Supplement |
Sachets of 5 grams of maltodextrin daily supplementation |
|