Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
comparing high flow nasal cannula , conventional oxygen tharapy and non invasive ventilation post-extubation period for patients mechanically ventilated due to respiratory failure regarding re-intubation rate, ICU outcome & 28 days mortality
patients with respiratory failure either type I or type II planned for extubation will be divided into 3 groups post extubation :
Group I: will receive high flow nasal cannula giving oxygen 60 litres / minute flow group II: will receive nasal cannula up to 10 litres / minute group III: will receive non invasive ventilation
Data of the patients will be collected for 28 days post-extubation and analysed
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High flow nasal cannula | Active Comparator | A device of high flow nasal cannula giving 60 litres / min flow |
|
| Conventional oxygen | Placebo Comparator | Nasal cannula giving oxygen up to 10 litres / minute |
|
| Non invasive ventilation | Active Comparator | non invasive ventilation with IPAP and EPAP |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High flow nasal cannula | Device | Device gives high flow oxygen comparable to non invasive ventilation and conventional oxygen therapy |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with post extubation respiratory failure | Number of participants with post extubation hypoxemia with or without hypercapnea | 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of ICU stay and mortality | Duration of ICU stay and incidence of mortality | 28 days |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Yasser Nassar, MD | Cairo University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine | Giza | 11345 | Egypt |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D012131 | Respiratory Insufficiency |
| ID | Term |
|---|---|
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D063087 | Noninvasive Ventilation |
| ID | Term |
|---|---|
| D012121 | Respiration, Artificial |
| D058109 | Airway Management |
| D013812 | Therapeutics |
| D012138 | Respiratory Therapy |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|