INTER-Regional COHORTE of Long Term Pancreatic Cancer Survivors

INTER-Regional COHORTE of Long Term Pancreatic Cancer Survivors

The study is particularly innovative as it will accurately analyze the microscopic characteristics of the stroma, tumor budding and mucin expression in adenocarcinomas of the pancreas, using a comparative approach of long-survivor/short-survival patients.

Inclusion Criteria:

• Patients > 18 years of age at diagnosis
• Primary pancreatic cancer patients operated on in one of the 4 centres between 2001 and 2016
• Histopathological diagnosis of excreto-pancreatic adenocarcinoma of the pancreas, ductal adenocarcinoma or classical adenocarcinoma
• Tissue blocks (FFPE) available (tumour/healthy tissue)
• Affiliated to a social security scheme

Exclusion Criteria:

• Absence of Primary Cancer Tissue Blocks (PCTBs)
• Paraffin block fixed in Bouin or AFA
• Patient Refusal
• Pancreatic cancer not corresponding to a conventional excretopancreatic adenocarcinoma such as: carcinoma on intraductal papillary mucinous neoplasm, endocrine tumor/carcinoma, acinar cell carcinoma, ...).
• Patient died due to post-surgical complications (death within 30 days post-surgery).
• Surgical resection of macroscopic R2 type.