Hypomagnesemia Associated With Proton-Pump Inhibitor Use

Hypomagnesemia Associated With Proton-Pump Inhibitor Use

Use of proton pump inhibitors has been associated with hypomagnesemia. However, various case-control or prospective studies have found conflicting results with regards to proton pump inhibitors use and development of hypomagnesemia. Our aim was to evaluate the likelihood that proton pump inhibitors contributed to severe hypomagnesemia in a retrospective cohort of patients admitted with severe hypomagenesemia. We also aimed to look for risk factors leading to development of hypomagnesemia amongst users of proton pump inhibitors

Inclusion Criteria:

• Patients admitted with hypomagnesemia (cases)
• Patients prescribed with proton pump inhibitors (controls)

Exclusion Criteria:

• Patients prescribed with less than three months duration of proton pump inhibitors (controls)