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| Name | Class |
|---|---|
| Reactive Robotics GmbH | UNKNOWN |
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Feasibility trial investigating robotic assisted early mobilization vs. early mobilization in critically ill patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Robotic assisted early mobilization | Experimental | Robotic assisted early mobilization started within 72 hours of ICU admission. |
|
| Early mobilization | Active Comparator | Early mobilization started within 72 hours of ICU admission without the use of a robotic assistance. Mobilization is done by personell. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Robotic-assisted early mobilization | Device | The early mobilization is done by robotic assistance devices. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Feasibility of early mobilization | Frequency of early mobilization performed by one health care provider during mechanical ventilation | Up to Day 5 |
| Measure | Description | Time Frame |
|---|---|---|
| Mobilization level | Mobilization level during mechanical ventilation using the ICU Mobility Scale (IMS) ranging from 0-10 | up to Day 5 |
| Mobilization duration | Duration of mobilzation sessions during mechanical ventilation |
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Inclusion Criteria:
Exclusion Criteria:
Translated with www.DeepL.com/Translator (free version)
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| Name | Affiliation | Role |
|---|---|---|
| Stefan J Schaller, MD | Charite University, Berlin, Germany | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Charité - Univiversitätsmedizin Berlin | Mitte | State of Berlin | 10117 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40414562 | Derived | Lorenz M, Langer N, Kloss P, Maechler M, Bald A, Warner L, Fuest K, Weiss B, Schaller SJ. ROBotic-assisted Early Mobilization in ventilated surgical critically ill patients (ROBEM-I)-A randomized, controlled, outcome-assessor-blinded pilot study. Anaesth Crit Care Pain Med. 2025 Aug;44(4):101549. doi: 10.1016/j.accpm.2025.101549. Epub 2025 May 23. |
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Anonymized data can be requested from the PI after publication of the study for scientific purpose.
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After publishing results.
Data will be shared to other researchers on reasonable request.
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| ID | Term |
|---|---|
| D016638 | Critical Illness |
| ID | Term |
|---|---|
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| ID | Term |
|---|---|
| D004434 | Early Ambulation |
| ID | Term |
|---|---|
| D012046 | Rehabilitation |
| D000359 | Aftercare |
| D003266 | Continuity of Patient Care |
| D005791 | Patient Care |
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Randomized, controlled, parallel-group, open label pilot trial
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| Early mobilization | Other | Early mobilization by health care professionals without robotic assistance. |
|
| up to Day 5 |
| Frequency of mobilization | Frequency of early mobilization during mechanical ventilation | up to Day 5 |
| Pain level | Pain level at mobilization using a numerical scale (NRS 0-10) or BPS 3-12 | up to Day 5 |
| Anxiety | Anxiety due to mobilization using a numerical scale (NRS 0-10) | up to Day 5 |
| Patient satisfaction with mobilization | Satisfaction with mobilization using a numerical scale (NRS 0-10) | Up to Day 5 |
| Inflammatory response | Zytokin change from before to after mobilization | Up to Day 5 |
| Health care provider assessment | Assessment of the satisfaction with the mobilization by the health care provider using Likert-Scales (1-5) | Up to Day 5 |
| Muscle wasting | Muscle wasting will be assessed using ultrasound measurement of the M. femoris | Up to Day5 |
| Oxygen consumption during mobilization | Oxygen consupmtion during mobilization will be measured using calorimetrie during mobilization | Up to Day 5 |
| Oesophageal pressure | Oesophageal pressure will be measured during mobilization | Up to Day 5 |
| Safety events | Frequency of safety events during mobilization | Up to Day 5 |
| D013812 |
| Therapeutics |