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| Name | Class |
|---|---|
| Istanbul University - Cerrahpasa | OTHER |
| Medipol University | OTHER |
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Multiple sclerosis (MS) is a complex neurodegenerative autoimmune disease. People with MS (PwMS) have low quality of life (QoL) and activities of daily living (ADL). Exercise is a safe and effective rehabilitation tool for PwMS. A structured and personalized exercise program can improve physical fitness, functional capacity, quality of life and modifiable disorders in PwMS. On the other hand, Telerehabilitation is an alternative rehabilitation method in PwMS. The purpose of this study is to investigate the effectiveness of exercise programs and telerehabilitation on ADL and QoL in PwMS, and compare the effects of supervised exercise and home-based exercise programs for the PwMS.
Participants are randomly assigned to the structured supervised exercise or structured home-based groups. Interventions in Group 1 (n=15) includes one session per day, 3 days a week over a 12-weeks structured exercise program under the supervision of a physical therapist. Group 2 (n=15) includes a 12-week structured home-based exercise program checked and controlled through telerehabilitation three times a week. All measurements pre-post intervention.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Supervised Exercise Group | Experimental | One session per day, 3 days per week over a 12-weeks structured exercise program under supervision of a physical therapist. |
|
| Telerehabilitation Group | Experimental | One session per day, 3 days per week over a 12-weeks structured exercise program through Telerehabilitation |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Structured Supervised Exercise | Behavioral | Structured Exercise Program under the supervision of Physical Therapist |
|
| Measure | Description | Time Frame |
|---|---|---|
| Functional Independence Measure (FIM) | FIM is a tool used for evaluation of primary ADL of people with disability. FIM items include self care, sphincter control, transfers, locomotion, communication, and social cognition subgroups. Grading is based on 7 points. 7: complete independence, 6: modified independence, 5, 4 and 3: modified dependence, 2 and 1: complete dependence. | Changes after 12 weeks |
| Nottingham Health Profile, First section (NHP-I) | NHP is a tool used for measuring and definition of QoL regarding the health status in general. NHP-I contains 38 yes/no statements, focusing on different aspects of the general health problems, including six dimensions of subjective health defined as physical abilities, pain, sleep, energy, emotional reaction, energy level and social isolation. Questions are evaluated according to the patients' yes/no responses and are scored between 0 and 100. High scores indicate high level health status in the specified item. Total scores are summed in all fields. | Changes after 12 weeks |
| Quality of life scale (QoLS) | QoLS is a standardized interview consisting of 41 questions clustered in four subscales: functional and economic scale, social and recreational scale, affect and life in general scale, and medical problems scale. Each question in the scale is evaluated over 5 points. (1 is negative at all times and 5 is the best response). | Changes after 12 weeks |
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Inclusion Criteria:
patients with:
Exclusion Criteria:
patients with:
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| Name | Affiliation | Role |
|---|---|---|
| Ela Tarakci, Professor | etarakci@istanbul.edu.tr | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Istanbul University-Cerrahpaşa | Istanbul | 34815 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D009103 | Multiple Sclerosis |
| ID | Term |
|---|---|
| D020278 | Demyelinating Autoimmune Diseases, CNS |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D003711 | Demyelinating Diseases |
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Participants will randomly assign to the structured supervised exercise or structured home-based groups. Randomization are done using Microsoft Excel 'RAND()' function.
| Structured telerehabilitation | Behavioral | Structured Exercise Program checked and controlled through telerehabilitation |
|
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |