Double Trigger in Patients With Low Proportion of Mature Oocytes

Double Trigger in Patients With Low Proportion of Mature Oocytes. A Randomized Controlled Trial

The aim of this randomized controlled trial is to determine whether co-administration of GnRH agonist and hCG for final oocyte maturation ( 40 and 34 h prior to oocyte retrieval , respectively) can increase the number of mature oocytes in patients with history of low proportion of mature oocytes in previous IVF cycle triggered by HCG.

Inclusion Criteria:

• Patients with history of low proportion of mature oocytes in previous IVF attempt (triggered by HCG).
• Patients with 6 to 15 mature follicles on the day oocyte trigger in the current IVF-ET attempt

Exclusion Criteria:

• Endometriosis
• PCOS