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| Name | Class |
|---|---|
| The Alfred | OTHER |
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Patients who are critically ill with COVID-19 requiring life support in an intensive care unit (ICU) have increased risk of morbidity and mortality. Currently the ICU community does not know what effect the disease, the ICU admission, physiotherapy interventions and life support have on their long-term quality of life and whether they can return to their pre-illness level of function following ICU.
COVID-Recovery will describe the physiotherapy interventions delivered to critically ill patients with COVID-19. In survivors, COVID-Recovery will utilise telephone follow-up of ICU survivors to assess disability-free survival and quality of life at 6 months after ICU admission. Additionally, COVID-Recovery will identify if there are predictors of disability-free survival. COVID-Recovery will aim to select up to 300 patients diagnosed with COVID-19 from ICUs in Australia. If they survive to hospital discharge, patients will be invited to receive a telephone questionnaire at 6 months after the ICU admission that aims to assess their long-term outcomes, including physical, cognitive and emotional function, quality of life, and whether they have been able to return to work following ICU discharge.
To describe the experience of critical illness in survivors of COVID-19 and their family members.
To explore and describe functional recovery, respiratory system function and respiratory health morbidity up to 6 months after ICU admission in persistently critically ill adults with COVID-19
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| Measure | Description | Time Frame |
|---|---|---|
| Disability-free survival | a composite measure of WHODAS 2.0 - 12 level and hospital survival | 6 months |
| Physiotherapy intervention | The physiotherapy interventions provided to patients with COVID-19 admitted to the ICU and health outcomes | During the ICU stay until 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Health status | Health related quality of life measured with EQ5D-5L score from 0 to 100 | 6 months |
| Global function | World Health Organization Disability Assessment Schedule 2.0 12L |
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Inclusion Criteria:
Persistent critical illness cohort
Exclusion Criteria:
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Critically ill patients with COVID-19 admitted to an intensive care unit
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| Name | Affiliation | Role |
|---|---|---|
| Carol Hodgson, PhD | Monash University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Canberra Hospital | Garran | Australian Capital Territory | 2605 | Australia | ||
| Royal Prince Alfred Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 35258437 | Derived | Hodgson CL, Higgins AM, Bailey MJ, Mather AM, Beach L, Bellomo R, Bissett B, Boden IJ, Bradley S, Burrell A, Cooper DJ, Fulcher BJ, Haines KJ, Hodgson IT, Hopkins J, Jones AYM, Lane S, Lawrence D, van der Lee L, Liacos J, Linke NJ, Gomes LM, Nickels M, Ntoumenopoulos G, Myles PS, Patman S, Paton M, Pound G, Rai S, Rix A, Rollinson TC, Tipping CJ, Thomas P, Trapani T, Udy AA, Whitehead C, Anderson S, Neto AS; COVID-Recovery Study Investigators and the ANZICS Clinical Trials Group. Comparison of 6-Month Outcomes of Survivors of COVID-19 versus Non-COVID-19 Critical Illness. Am J Respir Crit Care Med. 2022 May 15;205(10):1159-1168. doi: 10.1164/rccm.202110-2335OC. | |
| 34749756 |
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IPD will be shared if approved by the steering committee and with ethical approvals.
12 months after completion of the study for 12 months
Email the Chief Investigator
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| 6 months |
| Cognitive function | Montreal Cognitive Assessment Blind | 6 months |
| Anxiety and depression | Hospital Anxiety and Depression Scale | 6 months |
| Screening for post-traumatic distress | Impact of Events Scale Revised | 6 months |
| Work Status | WHODAS 2.0 | 6 months |
| Proportion of patients with COVID-19 who received physiotherapy in ICU | During the ICU stay until 28 days |
| The reported barriers to delivering physiotherapy interventions | Physiotherapist reported barriers to delivering the intervention | During the ICU stay until 28 days |
| Adverse events during physiotherapy interventions | Adverse events that require the intervention to be ceased for medical intervention | During the ICU stay until 28 days |
| Phenomenological data of the patient and family experience | Qualitative interviews | 6 months |
| Global function | Global Rating of Change | 6 months |
| Camperdown |
| New South Wales |
| 2050 |
| Australia |
| Concord Hospital | Concord | New South Wales | 2139 | Australia |
| St Vincent's Hospital Sydney | Darlinghurst | New South Wales | 2010 | Australia |
| Nepean Hospital | Kingswood | New South Wales | 2747 | Australia |
| St George Hospital | Kogarah | New South Wales | 2217 | Australia |
| John Hunter Hospital | New Lambton Heights | New South Wales | 2305 | Australia |
| Royal North Shore Hospital | Saint Leonards | New South Wales | 2065 | Australia |
| Westmead Hospital | Westmead | New South Wales | 2145 | Australia |
| The Prince Charles Hospital | Chermside | Queensland | 4032 | Australia |
| Royal Brisbane and Women's Hospital | Herston | Queensland | 4029 | Australia |
| Redcliffe Hospital | Redcliffe | Queensland | 4020 | Australia |
| Gold Coast Hospital | Southport | Queensland | 4215 | Australia |
| Princess Alexandra Hospital | Woolloongabba | Queensland | 4102 | Australia |
| Royal Adelaide Hospital | Adelaide | South Australia | 5000 | Australia |
| Launceston Hospital | Launceston | Tasmania | 7250 | Australia |
| Casey Hospital | Berwick | Victoria | 3806 | Australia |
| Box Hill Hospital (Eastern Health) | Box Hill | Victoria | 3128 | Australia |
| Monash Medical Centre | Clayton | Victoria | 3168 | Australia |
| Dandenong Hospital | Dandenong | Victoria | 3175 | Australia |
| St Vincent's Hospital Melbourne | Fitzroy | Victoria | 3065 | Australia |
| Footscray Hospital | Footscray | Victoria | 3011 | Australia |
| Frankston Hospital | Frankston | Victoria | 3199 | Australia |
| Austin Hospital | Heidelberg | Victoria | 3084 | Australia |
| Cabrini Health | Malvern | Victoria | 3144 | Australia |
| Australian New Zealand Intensive Care Research Centre | Melbourne | Victoria | 3004 | Australia |
| Royal Melbourne Hospital | Parkville | Victoria | 3050 | Australia |
| Alfred Hospital | Prahran | Victoria | 3004 | Australia |
| Sunshine Hospital | St Albans | Victoria | 3021 | Australia |
| Derived |
| Hodgson CL, Higgins AM, Bailey MJ, Mather AM, Beach L, Bellomo R, Bissett B, Boden IJ, Bradley S, Burrell A, Cooper DJ, Fulcher BJ, Haines KJ, Hopkins J, Jones AYM, Lane S, Lawrence D, van der Lee L, Liacos J, Linke NJ, Gomes LM, Nickels M, Ntoumenopoulos G, Myles PS, Patman S, Paton M, Pound G, Rai S, Rix A, Rollinson TC, Sivasuthan J, Tipping CJ, Thomas P, Trapani T, Udy AA, Whitehead C, Hodgson IT, Anderson S, Neto AS; COVID-Recovery Study Investigators and the ANZICS Clinical Trials Group. The impact of COVID-19 critical illness on new disability, functional outcomes and return to work at 6 months: a prospective cohort study. Crit Care. 2021 Nov 8;25(1):382. doi: 10.1186/s13054-021-03794-0. |
| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| D016638 | Critical Illness |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
| D014777 | Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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