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| Name | Class |
|---|---|
| Monash University | OTHER |
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Increasingly patients with critical illness requiring life support in an intensive care unit are surviving their hospital admission. Currently the investigators do not know what effect the ICU admission, and the life support, has on their long-term quality of life and whether they can return to their pre-illness level of function following ICU.
The investigators aim to test telephone follow-up of ICU survivors in assessing function and quality of life six months after ICU admission. Additionally, the investigators will identify if there are factors that lead to poor recovery. The investigators hope this can influence and change current ICU practice to improve recovery and long-term outcomes for patients.
The investigators aim to select a total of 300 patients from ICU, 75 patients from each of the four ICUs. If they survive to hospital discharge, patients and their relatives will receive a telephone questionnaire at 6 months after the ICU admission that aims to assess their long-term outcomes, including physical, cognitive and emotional function, quality of life, and whether they have been able to return to work following ICU.
The ICU Recovery program will measure psychological, functional and cognitive function and quality of life with health economic outcomes in critically ill patients 6 months after ICU admission. The initial pilot study will determine feasibility of the patient outcomes and measurement methods used. The study will consist of patients from three (3) Monash Partners ICUs (2 public and 1 private) as well as The Austin Hospital ICU. 10,000 ICU patients are managed by Monash Partners Academic Health Science Centre (MPAHSC) public and private hospitals each year, of which in the region of 8,500 patients survive. These patients add to the community burden and also influence community and rehabilitation costs. Ultimately, our goal is to establish a national National Health & Medical Research Council (NHMRC) -funded interventional study, led by Monash Partners. Our aim is to improve long-term patient outcomes through: improving sedation practices, delirium prevention, neurocognitive stimulation, early mobilisation, post-ICU follow-up, and functional and psychological rehabilitation. This study is required for the evaluation of hospital and post-ICU rehabilitation practice as there is insufficient evidence to alter current clinical practice.
OBJECTIVES
Primary Aim:
To determine the feasibility of the multi-centre ICU Recovery study using telephone follow-up to assess quality of life, global, psychological, cognitive and physical outcomes at six months following ICU admission.
Secondary Aims
Tertiary Aims
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intensive care survivors | Patients surviving an admission to an intensive care unit |
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| Measure | Description | Time Frame |
|---|---|---|
| Feasibility of telephone interview | Determine feasibility of using a telephone interview to ascertain the functional recovery and quality of life and critically ill ICU survivors. | At completion of telephone interview, expected average of 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Health related quality of life | Health related quality of life (HRQOL) measured with EuroQol five dimensions questionnaire (EQ-5D) before ICU (retrospective survey) and at 6 months (prospective survey) | At telephone interview, conducted at an expected average of 6 months following discharge from the Intensive Care Unit |
| Measure | Description | Time Frame |
|---|---|---|
| Pre-ICU function | Pre-ICU function measured with EuroQol five dimensions questionnaire (EQ-5D) and work details | At telephone interview, conducted at an expected average of 6 months following discharge from the Intensive Care Unit |
| Global function |
Inclusion Criteria:
Exclusion Criteria:
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300 critically ill patients who were mechanically ventilated >24 hours in an intensive care unit who have survived to hospital discharge.
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| Name | Affiliation | Role |
|---|---|---|
| Carol Hodgson, PhD MRes | ANZIC-RC | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Monash Medical Centre | Clayton | Victoria | 3168 | Australia | ||
| The Austin Hospital |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28534110 | Derived | Hodgson CL, Udy AA, Bailey M, Barrett J, Bellomo R, Bucknall T, Gabbe BJ, Higgins AM, Iwashyna TJ, Hunt-Smith J, Murray LJ, Myles PS, Ponsford J, Pilcher D, Walker C, Young M, Cooper DJ. The impact of disability in survivors of critical illness. Intensive Care Med. 2017 Jul;43(7):992-1001. doi: 10.1007/s00134-017-4830-0. Epub 2017 May 22. |
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Global function at 6 months, assessed with World Health Organization Disability Assessment Schedule (WHODAS)
| At telephone interview, conducted at an expected average of 6 months following discharge from the Intensive Care Unit |
| Physical activity | Physical activity at 6 months, assessed with International Physical Activity Questionnaire (IPAQ). | At telephone interview, conducted at an expected average of 6 months following discharge from the Intensive Care Unit |
| Cognitive function | Cognitive function at 6 months, assessed with Telephone Interview for Cognitive Status (TICS). | At telephone interview, conducted at an expected average of 6 months following discharge from the Intensive Care Unit |
| Anxiety and depression | Anxiety and depression at 6 months will be assessed with the Hospital Anxiety and Depression Scale (HADS) and the Impact of Event Scale (IES-R) | At telephone interview, conducted at an expected average of 6 months following discharge from the Intensive Care Unit |
| Return to work | Return to work at 6 months | At telephone interview, conducted at an expected average of 6 months following discharge from the Intensive Care Unit |
| Heidelberg |
| Victoria |
| 3084 |
| Australia |
| Cabrini Hospital | Malvern | Victoria | 3144 | Australia |
| The Alfred Hospital | Melbourne | Victoria | 3004 | Australia |
| Epworth Hospital | Richmond | Victoria | 3121 | Australia |