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The aim of this study was to evaluate the survival rate and healing time of compromised teeth and seriously compromised teeth that were endodontically treated in patients which received bisphosphonate therapy . Clinical complications, success and survival rate was reported. Mean clinical parameters, clinical symptoms and presence of periapical radilucency were recorded.
The study was conducted in one University Endodontic Clinical Department - Dental School between January 2009 and December 2017.
Root canal treatment was performed according previously reported operative protocols.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| BPS group | patients under Bisphosphonate therapy for at least 24 months |
| |
| healthy patients | healthy patients not assuming with no previous Bisphosphonate assumption |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Root canal treatment | Procedure | Root canal treatment using a standard manual k file instrumentation and carrier-based root canal filling technique |
|
| Measure | Description | Time Frame |
|---|---|---|
| health patients | assessment of periapical index (PAI) | 5 years |
| Measure | Description | Time Frame |
|---|---|---|
| Complications | extraction periapical re exacerbation during before the endline ( 5 years) | 5 years |
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Inclusion Criteria:
Exclusion Criteria:
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Similar geographic provenience
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24908421 | Result | Pirani C, Chersoni S, Montebugnoli L, Prati C. Long-term outcome of non-surgical root canal treatment: a retrospective analysis. Odontology. 2015 May;103(2):185-93. doi: 10.1007/s10266-014-0159-0. Epub 2014 Jun 8. | |
| 29432651 | Result | Prati C, Pirani C, Zamparini F, Gatto MR, Gandolfi MG. A 20-year historical prospective cohort study of root canal treatments. A Multilevel analysis. Int Endod J. 2018 Sep;51(9):955-968. doi: 10.1111/iej.12908. Epub 2018 Mar 7. |
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| ID | Term |
|---|---|
| D059266 | Bisphosphonate-Associated Osteonecrosis of the Jaw |
| D010482 | Periapical Abscess |
| D019553 | Tooth, Nonvital |
| ID | Term |
|---|---|
| D010020 | Osteonecrosis |
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D007571 | Jaw Diseases |
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| D009057 |
| Stomatognathic Diseases |
| D009336 | Necrosis |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D000038 | Abscess |
| D013492 | Suppuration |
| D007239 | Infections |
| D010485 | Periapical Periodontitis |
| D010483 | Periapical Diseases |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D010518 | Periodontitis |
| D003788 | Dental Pulp Diseases |
| D014076 | Tooth Diseases |