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This is a 12-week, randomized nutritional intervention study to determine the effect of legumes consumption on body weight in obese subjects.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Legume enriched diet group | Experimental |
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| Usual diet group | No Intervention |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Legume enriched diet group | Behavioral |
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| Measure | Description | Time Frame |
|---|---|---|
| Changes of BMI | Changes of weight in kilograms was assessed before and after the intervention. Changes of height in meters was assessed before and after the intervention. Weight and height were combined to report BMI in kg/m^2. | 12 weeks |
| Changes of Insulin Resistance (IR) | Changes of fasting serum glucose in mmol/L was assessed before and after the intervention. Changes of fasting insulin in μIU/mL was assessed before and after the intervention. Fasting insulin and fasting glucose were combined to report IR using the following equation: homeostasis model assessment (HOMA)-IR=[fasting insulin (μIU/mL)×fasting glucose (mmol/L)] /22.5. | 12 weeks |
| Changes of lipid profiles | Triglyceride in mg/dL was assessed before and after the intervention. Total-cholesterol in mg/dL was assessed before and after the intervention. HDL-cholesterol in mg/dL was assessed before and after the intervention. LDL-cholesterol was indirectly estimated using the friedewald formula: LDL-cholesterol= total-cholesterol-[HDL-cholesterol+(triglycerides/5)]. | 12 weeks |
| Changes of serum high C-reactive | Changes of serum high C-reactive in mg/L was assessed before and after the intervention. | 12 weeks |
| Changes of urinary 8-epi-PGF2α | Changes of urinary 8-epi-PGF2α in pg/mg creatinine was assessed before and after the intervention. | 12 weeks |
| Changes of adiponectin | Changes of adiponectin in ng/mL was assessed before and after the intervention. |
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Inclusion Criteria:
Exclusion Criteria:
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| ID | Term |
|---|---|
| D009765 | Obesity |
| D001835 | Body Weight |
| D007333 | Insulin Resistance |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| 12 weeks |
| D012816 |
| Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |