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The management of patients with SARS-CoV2 in respiratory distress can expose to corneal or retinal lesions induced by the stay in intensive care.
Examination by ophthalmologists would make it possible to detect the most of the ophthalmologic problems known in intensive care and to provide an early, preventive or curative therapeutic response when possible, in order to avoid irreversible visual loss.
The object of the research is to assess the presence and the importance of surface ophthalmologic lesions, the presence and the importance of retinal or optic nerve lesions, in order to improve the monitoring and primary prevention of this population
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Ophthalmologic exam | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ophthalmologic exam | Procedure | Direct exam and Slit lamp exam Shirmer test Retinophotography At inclusion, day 7, day 14 and discharge from hospital |
|
| Measure | Description | Time Frame |
|---|---|---|
| Describe ophthalmologic damage to the cornea with direct exam at day 0 | Direct exam | Day 0 |
| Describe ophthalmologic damage to the cornea with direct exam at day 7 | Direct exam | Day 7 |
| Describe ophthalmologic damage to the cornea with direct exam at day 14 | Direct exam | Day 14 |
| Describe ophthalmologic damage to the cornea with direct exam at discharge of hospital | Direct exam | Discharge of hospital, up to 3 months |
| Describe ophthalmologic damage to the cornea with slit lamp exam at day 0 | Slit lamp exam | Day 0 |
| Describe ophthalmologic damage to the cornea with slit lamp exam at day 7 | Slit lamp exam | Day 7 |
| Describe ophthalmologic damage to the cornea with slit lamp exam at day 14 | Slit lamp exam | Day 14 |
| Describe ophthalmologic damage to the cornea with slit lamp exam at discharge of hospital | Slit lamp exam | Discharge of hospital, up to 3 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jean Michel DEVYS, MD | Fondation Adolphe de Rothschild | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fondation Adolphe de Rothschild | Paris | 75019 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 34174393 | Result | Stephan S, Cohen F, Salviat F, Thevenin S, Devys JM, Cochereau I, Gabison E. Evaluation of the impact of intensive care support for COVID-19 on the ocular surface in a prospective cohort of 40 eyes. Ocul Surf. 2021 Oct;22:13-14. doi: 10.1016/j.jtos.2021.06.008. Epub 2021 Jun 23. No abstract available. |
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| ID | Term |
|---|---|
| D000086382 | COVID-19 |
| ID | Term |
|---|---|
| D011024 | Pneumonia, Viral |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |
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| Describe tear film anomalies at day 0 | Shirmer test | Day 0 |
| Describe tear film anomalies at day 7 | Shirmer test | Day 7 |
| Describe tear film anomalies at day 14 | Shirmer test | Day 14 |
| Describe tear film anomalies at discharge of hospital | Shirmer test | Discharge of hospital, up to 3 months |
| Describe ophthalmologic damage to the retina at day 0 | Retinophotography | Day 0 |
| Describe ophthalmologic damage to the retina at day 7 | Retinophotography | Day 7 |
| Describe ophthalmologic damage to the retina at day 14 | Retinophotography | Day 14 |
| Describe ophthalmologic damage to the retina at discharge of hospital | Retinophotography | Discharge of hospital, up to 3 months |
| Describe ophthalmologic damage to the optic nerve at day 0 | Retinophotography | Day 0 |
| Describe ophthalmologic damage to the optic nerve at day 7 | Retinophotography | Day 7 |
| Describe ophthalmologic damage to the optic nerve at day 14 | Retinophotography | Day 14 |
| Describe ophthalmologic damage to the optic nerve at discharge of hospital | Retinophotography | Discharge of hospital, up to 3 months |
| D014777 |
| Virus Diseases |
| D018352 | Coronavirus Infections |
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |