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The study aims to assess the incidence and the risk factors of nephrocalcinosis in very preterm infants using patient data collected during hospitalisation at the Neonatology Centre.
Nephrocalcinosis in preterm infants develops as a result of imbalance between the factors promoting or inhibiting formation of kidney stones. It is caused by intensive treatment as well as functional and morphological kidney immaturity. There is a correlation between the prevalence of nephrocalcinosis and low gestational age.
The study aims prospectively to assess the incidence and the risk factors of nephrocalcinosis in very preterm infants less than 32 weeks of gestation.
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| Measure | Description | Time Frame |
|---|---|---|
| The incidence of nephrocalcinosis in very preterm infants less than 32 weeks of gestation | Kidney ultrasound results will divide preterm infants in the group with and without nephrocalcinosis (control). | 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| Compare demographic, clinical, biochemical and treatment results between nephrocalcinosis and the control (without nephrocalcinosis) groups. | Patients data (demographic, clinical, biochemical and treatment results) collected during hospitalisation at the Neonatology Centre will be compared between nephrocalcinosis and control group. | 3 years |
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Inclusion Criteria:
Exclusion Criteria:
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The study population is a group of very preterm infants less than 32 weeks of gestation during hospitalisation at the Neonatology Centre.
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| Name | Affiliation | Role |
|---|---|---|
| Rasa Garunkstiene, PhD | Vilnius University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Vilnius University, Neonatology Centre | Vilnius | 08464 | Lithuania |
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| ID | Term |
|---|---|
| D009397 | Nephrocalcinosis |
| D047928 | Premature Birth |
| ID | Term |
|---|---|
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
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| To evaluate the dynamics of nephrocalcinosis at 6 and 12 months of corrected age. | Nephrologist consultation of the infants with nephrocalcinosis at 6 and 12 months of corrected age | 6 and 12 months of corrected age |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D002114 | Calcinosis |
| D002128 | Calcium Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D007752 | Obstetric Labor, Premature |
| D007744 | Obstetric Labor Complications |
| D011248 | Pregnancy Complications |