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The aim of this study is to test the hyaluronic acid hydrogel impact on the healing acceleration of xenogenic bone substitutes used in ridge preservation.
Following tooth extraction, bone particles are mixed with the hyaluronic acid gel and grafted in the tooth socket. at the implant placement phase, a cone beam computer assisted tomography file is recorded in order to compare it with the baseline and a biopsy to evaluate the histological consequences.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Radiological assessement | Experimental | Two CBCTs were recorded and compared, one at the baseline and the other at 4 months post-op. The bone resorption was quantified and analyzed using ITK-SNAP software |
|
| Histomorphometric analysis | Experimental | During implant placement (4 months after the bone grafting), a bone biopsy is collected and stained with several colorants to analyze the biological bone healing |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Ridge preservation: Tooth extration and immediat bone grafting in the socket | Procedure | Following the tooth extraction, the socket is filled with a mixture of xenogenic bone and hyaluronic acid and sealed with an epithelio-connective arrested from the maxillary palate |
| Measure | Description | Time Frame |
|---|---|---|
| Radiological assessement of the boe resorption | the baseline if the CBCT is compared to the 4 months post-op to assess the bone resorption | 4 months |
| Histomorphometric analysis | During implant placement, a bone biopsy is harvested and stained with different colorants to assess microscopically the biological healing | 4 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Ronald J Younes, Phd | Head of oral surgery department, facuty of dentistry ,Universite SainT Joseph-Beyrouth | Study Director |
| Bachar A Husseini, DDS | Department of oral surgery, facuty of dentistry ,Universite SainT Joseph-Beyrouth | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Saint-Joseph university | Beirut | Lebanon | 1104 2020 | Lebanon | ||
| Universte Saint Joseph-Beyrouth |
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| ID | Term |
|---|---|
| D001862 | Bone Resorption |
| D016388 | Tooth Loss |
| ID | Term |
|---|---|
| D001847 | Bone Diseases |
| D009140 | Musculoskeletal Diseases |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
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| Beirut |
| Lebanon |
| D009057 |
| Stomatognathic Diseases |
| D014076 | Tooth Diseases |