Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
A sulcular incision will be made through each recession area and the tissues will be gradually undermined including the base of the interdental papilla. At the recession sites rhEGF incorporated absorbable collagen membrane will be gradually manipulated into the pouch through the tunnel till it covers the recession sites and will be stabilized with sutures.
IN TEST SITE :
Local anesthesia will be administered and Vertical incisions will be given at interdental papillae away from recession defect site and a pouch will be created. A sulcular incision will be made through each recession area and the tissues will be gradually undermined including the base of the interdental papilla. At the recession sites rhEGF incorporated absorbable collagen membrane will be gradually manipulated into the pouch through the tunnel till it covers the recession sites and will be stabilized with sutures.
IN CONTROL SITE:
Same procedure will be done as the test site but plain collagen membrane will be gradually manipulated into the pouch through the tunnel till it covers the recession sites and will be stabilized with sutures.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| EGF impregnated in collagen membrane | Experimental | EGF impregnated in collagen membrane is placed in gingival recession defects |
|
| plain collagen membrane | Active Comparator | plain collagen membrane is placed in gingival recession defects |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| RhEGF | Drug | The EGF impregnated membrane will be placed upon the recession site and will be stabilized by suturing it to the lingual papillae using 4-0 absorbable sutures. The flap will be coronally advanced as far as possible to cover the membrane and will be sutured to the buccal interdental papillae with 4-0 absorbable sutures (Trulenetm, Healthium Medtech Pvt Ltd, Bangalore, India). Standard recall and maintenance regimen will be followed and subjects will be encouraged to report to the department on a monthly basis. |
| Measure | Description | Time Frame |
|---|---|---|
| Recession depth (RD) | Recession depth (RD) - measured from cementoenamel junction to most apical extension of gingival margin. | Base line to 6months. |
| Measure | Description | Time Frame |
|---|---|---|
| Width of keratinized gingiva (KGW) | Width of keratinized gingiva (KGW) - distance between gingival margin and mucogingival junction will be evaluated. | Base line to 6months. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| R V Chandra, MDS;DNB;PHD | Contact | 9908183071 | viswachandra@hotmail.com |
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| R V Chandra | Recruiting | Hyderabad | Telangana | 509002 | India |
Not provided
| ID | Term |
|---|---|
| D010518 | Periodontitis |
| D005889 | Gingival Recession |
| ID | Term |
|---|---|
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D005882 | Gingival Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D035061 | Control Groups |
| ID | Term |
|---|---|
| D015340 | Epidemiologic Research Design |
| D004812 | Epidemiologic Methods |
| D008919 | Investigative Techniques |
| D012107 | Research Design |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
|
| Plain Collagen | Drug | A collagen membrane without FGF-2 will be used. |
|
|
| D055093 |
| Periodontal Atrophy |
| D008722 | Methods |