Bone Morphogenetic Protein-2 In Grade II Furcation Defects.

Recombinant Human Bone Morphogenetic Protein-2 In Absorbable Sponge Vs Platelet Rich Fibrin (PRF) In Grade Ii Furcation Defects - A Randomized Controlled Trial

The present study evaluated clinically and radiographically the regenerative potential of rhBMP-2 in absorbable sponge and PRF in Grade II furcation.

44 subjects were enrolled in the study. PPD, CAL, plaque index and gingival index were recorded and the evaluation of bone fill was performed after 6 months by using ImageJ® software. After 6 months, the bone fill obtained with rhBMP-2 was higher when compared to PRF. From this trial conducted over a period of 6 months, the unique properties associated with rhBMP-2 in absorbable sponge makes it a potential agent to be used as a graft material for Grade II furcation defects.

Inclusion Criteria:

• Systemically healthy male and female patients of age group 20-55 yrs
• grade II furcation involvement and probing pocket depth of ≥5mm

Exclusion Criteria:

• Medically compromised patients
• subjects who underwent radiotherapy or chemotherapy in the past 12 months
• patients having uncontrolled periodontal disease and
• subjects smoking ≥10 cigarettes per day were excluded