Perioperative Muscle Relaxant and Postoperative Outcomes

Effect of Perioperative Muscle Relaxant Model on Postoperative Outcomes in Chinese Patients

Muscle relaxant is usually needed for surgery. However, the optimal depth of neuro-muscular blockade is still on debate. Deep neuro-muscular blockade may benefit the patients during surgery, but may increase the risk of residual blockade after surgery. Residual blockade has been reported to increase risk of morbidity. In this study, we tend to observe the postoperative outcomes in patients undergoing abdominal surgery under general anesthesia. And to compare the outcomes in patients received different depth of neuro-muscular blockade.

Inclusion Criteria:

• Age ≥18 years old
• Body mass <18 kg/m2
• American Society of Anesthesiologists status I-II
• Patients scheduled for elective laparoscopic colorectal or urological surgery
• Patients received general anesthesia and muscle relaxant
• Patients with written informed consent.

Exclusion Criteria:

• Second surgery during the same admission.
• Outpatient surgery
• Retroperitoneal laparoscopic surgery
• Patients scheduled for mechanical ventilation after surgery
• Patients scheduled for muscle relaxant other than rocuronium
• Patients with pregnancy or planned for breeding
• Patients who are involved in other studies