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| Name | Class |
|---|---|
| Massachusetts General Hospital | OTHER |
| Stanford University | OTHER |
| Yale University | OTHER |
| Massachusetts Institute of Technology |
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Recent data have shown that covid19 is disproportionately infecting and killing African Americans and Latinx people in the United States. The aim of the study is to determine which messages are most effective at increasing knowledge and changing behaviors that can protect individuals and their communities from the virus. To accomplish this aim, we plan to recruit approximately 20,000 Hispanic and African-American individuals and randomly assign them to videos that vary either the sender or the framing of the message, while providing the relevant public health information.
The following procedures will be followed. The research subjects will participate online.
Doctors from MGH who express interest in participating will record messages according to our scripts (US Doctors Script African American, US Doctors Script Latinx). They will be instructed to film several different versions each.
We will recruit a sample of Latinx and African American study participants from across the country through Lucid, an online survey firm that has access to a large subject pool.
Participants will first read a consent script and give us their informed consent (US Doctors Messaging Consent)
Participants will then navigate through the following steps
The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control - CDC - Mask (Control) - Concordant | Experimental | Control Intro, CDC Social Distancing, Mask Control version delivered by minority doctor of same background as the recipient - other definitions are similar |
|
| Control - CDC - Mask (Control) - Discordant | Experimental | Control Intro, CDC Social Distancing, Mask Control version delivered by majority doctor of different background as the recipient - other definitions are similar |
|
| Control - MGH - Mask (Control) - Concordant | Experimental | Control Intro, MGH Social Distancing, Mask Control version delivered by concordant doctor |
|
| Control - MGH - Mask (Control) - Discordant | Experimental | Control Intro, MGH Social Distancing, Mask Control version delivered by discordant doctor |
|
| Ack. Discrimination- MGH - Mask (Control) - Concordant | Experimental | Introduction Acknowledges past discrimination, MGH doctor talks about Social Distancing, Mask Control all by concordant MD |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Messaging | Behavioral | o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| Measure | Description | Time Frame |
|---|---|---|
| Incidence Rate for Knowledge Gaps: Control vs. Any Intervention | Incidence rate for knowledge gaps is the count of knowledge gaps divided by the maximum possible count: 7 | The outcome was measured immediately following the intervention in the 15-minute baseline survey. |
| Incidence Rate for Information-seeking Behavior: Control vs. Any Intervention | Incidence rate for Information-seeking behavior is the count of links demanded divided by the maximum possible count: 10 | The outcome was measured immediately following the intervention in the 15-minute baseline survey. |
| Incidence Rate for Knowledge Gaps by Intervention | Incidence rate for knowledge gaps is the count of knowledge gaps divided by the maximum possible count: 7 | The outcome was measured immediately following the intervention in the 15-minute baseline survey. |
| Incidence Rate for Information-seeking Behavior by Intervention | Incidence rate for Information-seeking behavior is the count of links demanded divided by the maximum possible count: 10 | The outcome was measured immediately following the intervention in the 15-minute baseline survey. |
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Inclusion Criteria: Hispanic and African-American adult individuals, men and women - oversample of those with less completed education Exclusion Criteria: children, those who do not identify as above
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| JPAL North America | Cambridge | Massachusetts | 02138 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33347320 | Derived | Alsan M, Stanford FC, Banerjee A, Breza E, Chandrasekhar AG, Eichmeyer S, Goldsmith-Pinkham P, Ogbu-Nwobodo L, Olken BA, Torres C, Sankar A, Vautrey PL, Duflo E. Comparison of Knowledge and Information-Seeking Behavior After General COVID-19 Public Health Messages and Messages Tailored for Black and Latinx Communities : A Randomized Controlled Trial. Ann Intern Med. 2021 Apr;174(4):484-492. doi: 10.7326/M20-6141. Epub 2020 Dec 21. |
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Generally, economists will post code and de-identified data when the findings are published
Generally, social scientists post code and de-identified data when the findings are published
To be determined, if published alongside the paper data and code may be gated.
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The trial sample was enrolled from 13 May 2020 through 26 May 2020. Of 35,987 persons screened, 20,925 were eligible for participation (15,062 who would have been eligible were excluded because the demographic quotas were met); 5,450 individuals did not consent or failed both basic attention checks, and 1,208 left the survey before randomization. Out of 14,267 participants enrolled and randomized,123 participants did not answer one or more baseline questions and were excluded from analysis.
Individuals were recruited throughout the United States by the survey company Lucid from 13 May to 26 May 2020. Only persons aged 18 years or older and self-identifying as Black or Latinx were eligible.
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| ID | Title | Description |
|---|---|---|
| FG000 | Control - CDC - Mask (Control) - Concordant | Control Intro, CDC Social Distancing, Mask Control version delivered by minority doctor of same background as the recipient - other definitions are similar Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG001 | Control - CDC - Mask (Control) - Discordant | Control Intro, CDC Social Distancing, Mask Control version delivered by majority doctor of different background as the recipient - other definitions are similar Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG002 | Control - MGH - Mask (Control) - Concordant | Control Intro, MGH Social Distancing, Mask Control version delivered by concordant doctor Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG003 | Control - MGH - Mask (Control) - Discordant | Control Intro, MGH Social Distancing, Mask Control version delivered by discordant doctor Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG004 | Ack. Discrimination- MGH - Mask (Control) - Concordant | Introduction Acknowledges past discrimination, MGH doctor talks about Social Distancing, Mask Control all by concordant MD Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG005 | Ack. Discrimination- MGH - Mask (Control) - Discordant | Introduction Acknowledges past discrimination, MGH doctor talks about Social Distancing, Mask Control all by discordant MD Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG006 | Ack. Econ. Circumstance- MGH - Mask (Control ) Concordant | Intro econ. circumstance -MGH - Mask (Control ) Concordant Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG007 | Ack. Econ. Circumstance - MGH - Mask (Control ) Discordant | Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG008 | Control Intro - CDC - Mask (antiStigma) Concordant | Control Intro - CDC - Mask (antiStigma) Concordant messenger Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG009 | Control Intro - CDC - Mask (antiStigma) Discordant | Control Intro - CDC - Mask (antiStigma) discordant messenger Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG010 | Control - MGH - MaskS (antiStigma) Concordant Messenger | Control - MGH - MaskS (antiStigma) Concordant sender Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG011 | Control- MGH-MaskS (antiStigma) Discordant Messenger | Control - MGH - MaskS (antiStigma) Discordant sender Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG012 | Ack. Discrimination - MGH - MaskS (antiStigma) Concordant | Acknowledge Discrimination - MGH - MaskS (antiStigma) Concordant sender Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG013 | Ack. Discrimination - MGH - MaskS (antiStigma) Discordant | Acknowledge Discrimination - MGH - MaskS (antiStigma) Discordant sender Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG014 | Ack. Econ Hardship- MGH - Mask (antiStigma) Concordant | Acknowledge Econ Hardship- MGH - Mask (antiStigma) Concordant sender Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG015 | Ack. Econ Hardship- MGH - Mask (antiStigma) Discordant | Acknowledge Econ Hardship- MGH - Mask (antiStigma) discordant sender Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| FG016 | Info Later - Pure Control | This group will not receive the videos but will receive information later. Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
| Title | Milestones | Reasons Not Completed | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Overall Study |
|
Any intervention was indeed an arm that included each sub arm of different types of message that we tested against a control and pre-specified in our study protocol and analysis plan to combine arms for analysis.
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| ID | Title | Description |
|---|---|---|
| BG000 | Study Participants - Control | Study participants who are assigned to a pure control group |
| BG001 | Study Participants - Any Intervention | Study participants who are assigned to any intervention groups |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age, Continuous | Mean |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Incidence Rate for Knowledge Gaps: Control vs. Any Intervention | Incidence rate for knowledge gaps is the count of knowledge gaps divided by the maximum possible count: 7 | Any intervention was indeed an arm that included each sub arm of different types of message that we tested against a control and pre-specified in our study protocol and analysis plan to combine arms for analysis. | Posted | Mean | 95% Confidence Interval | proportion of knowledge gaps | The outcome was measured immediately following the intervention in the 15-minute baseline survey. |
|
14 days
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Control - CDC - Mask (Control) - Concordant | Control Intro, CDC Social Distancing, Mask Control version delivered by minority doctor of same background as the recipient - other definitions are similar Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
|
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Participants' behavior was not directly observed, outcomes were measured immediately postintervention in May 2020, and online recruitment may not be representative.
| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Pierre-Luc Vautrey | Massachusetts Institute of Technology | (617) 258-7013 | vautrey@mit.edu |
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| Type | Includes Protocol | Includes SAP | Includes ICF | Document Label | Document Date | Document Uploaded Date | Document File Name |
|---|---|---|---|---|---|---|---|
| Prot_SAP | Yes | Yes | No | Study Protocol and Statistical Analysis Plan | May 14, 2020 | Jun 23, 2021 | Prot_SAP_001.pdf |
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| ID | Term |
|---|---|
| D018352 | Coronavirus Infections |
| ID | Term |
|---|---|
| D003333 | Coronaviridae Infections |
| D030341 | Nidovirales Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
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| OTHER |
| Harvard University | OTHER |
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| Ack. Discrimination- MGH - Mask (Control) - Discordant | Experimental | Introduction Acknowledges past discrimination, MGH doctor talks about Social Distancing, Mask Control all by discordant MD |
|
| Ack. econ. circumstance- MGH - Mask (Control ) Concordant | Experimental | Intro econ. circumstance -MGH - Mask (Control ) Concordant |
|
| Ack. econ. circumstance - MGH - Mask (Control ) Discordant | Experimental |
|
| Control Intro - CDC - Mask (antiStigma) Concordant | Experimental | Control Intro - CDC - Mask (antiStigma) Concordant messenger |
|
| Control Intro - CDC - Mask (antiStigma) Discordant | Experimental | Control Intro - CDC - Mask (antiStigma) discordant messenger |
|
| Control - MGH - MaskS (antiStigma) Concordant messenger | Experimental | Control - MGH - MaskS (antiStigma) Concordant sender |
|
| Control- MGH-MaskS (antiStigma) Discordant messenger | Experimental | Control - MGH - MaskS (antiStigma) Discordant sender |
|
| Ack. Discrimination - MGH - MaskS (antiStigma) Concordant | Experimental | Acknowledge Discrimination - MGH - MaskS (antiStigma) Concordant sender |
|
| Ack. Discrimination - MGH - MaskS (antiStigma) Discordant | Experimental | Acknowledge Discrimination - MGH - MaskS (antiStigma) Discordant sender |
|
| Ack. Econ Hardship- MGH - Mask (antiStigma) Concordant | Experimental | Acknowledge Econ Hardship- MGH - Mask (antiStigma) Concordant sender |
|
| Ack. Econ Hardship- MGH - Mask (antiStigma) Discordant | Experimental | Acknowledge Econ Hardship- MGH - Mask (antiStigma) discordant sender |
|
| Info later - Pure Control | Placebo Comparator | This group will not receive the videos but will receive information later. |
|
|
| BG002 | Total | Total of all reporting groups |
| years |
|
| Sex: Female, Male | Count of Participants | Participants |
|
| Race/Ethnicity, Customized | Count of Participants | Participants |
|
| Region of Enrollment | Number | participants |
|
| Household size | Mean | Standard Deviation | person |
|
| Education index | Education index is an integer capturing the highest level of education attained scored on a scale of 1 (third grade or less) to 11 (doctorate). | Mean | Standard Deviation | scores on a scale |
|
| Likely to run out of money because of COVID-19 | Count of Participants | Participants |
|
| Trouble paying for food | Count of Participants | Participants |
|
| Stratum | Count of Participants | Participants |
|
| Hispanic origin | The "Hispanic Origin" question is only applicable to Latinx participants. | Count of Participants | Participants |
|
Study participants who are assigned to any intervention groups |
|
|
| Primary | Incidence Rate for Information-seeking Behavior: Control vs. Any Intervention | Incidence rate for Information-seeking behavior is the count of links demanded divided by the maximum possible count: 10 | Any intervention was indeed an arm that included each sub arm of different types of message that we tested against a control and pre-specified in our study protocol and analysis plan to combine arms for analysis. | Posted | Mean | 95% Confidence Interval | proportion of links | The outcome was measured immediately following the intervention in the 15-minute baseline survey. |
|
|
|
| Primary | Incidence Rate for Knowledge Gaps by Intervention | Incidence rate for knowledge gaps is the count of knowledge gaps divided by the maximum possible count: 7 | Each intervention indicated in Arm/Group Title was indeed an arm that included each sub arm of different types of message that we tested Arm A against Arm B, or vice versa, and pre-specified in our study protocol and analysis plan to combine arms for analysis. Arms A and B are indicated in each Arm/Group Title. | Posted | Mean | 95% Confidence Interval | proportion of knowledge gaps | The outcome was measured immediately following the intervention in the 15-minute baseline survey. |
|
|
|
| Primary | Incidence Rate for Information-seeking Behavior by Intervention | Incidence rate for Information-seeking behavior is the count of links demanded divided by the maximum possible count: 10 | Each intervention indicated in Arm/Group Title was indeed an arm that included each sub arm of different types of message that we tested Arm A against Arm B, or vice versa, and pre-specified in our study protocol and analysis plan to combine arms for analysis. Arms A and B are indicated in each Arm/Group Title. | Posted | Mean | 95% Confidence Interval | proportion of links | The outcome was measured immediately following the intervention in the 15-minute baseline survey. |
|
|
|
| 0 |
| 784 |
| 0 |
| 784 |
| 0 |
| 784 |
| EG001 | Control - CDC - Mask (Control) - Discordant | Control Intro, CDC Social Distancing, Mask Control version delivered by majority doctor of different background as the recipient - other definitions are similar Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 791 | 0 | 791 | 0 | 791 |
| EG002 | Control - MGH - Mask (Control) - Concordant | Control Intro, MGH Social Distancing, Mask Control version delivered by concordant doctor Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 780 | 0 | 780 | 0 | 780 |
| EG003 | Control - MGH - Mask (Control) - Discordant | Control Intro, MGH Social Distancing, Mask Control version delivered by discordant doctor Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 778 | 0 | 778 | 0 | 778 |
| EG004 | Ack. Discrimination- MGH - Mask (Control) - Concordant | Introduction Acknowledges past discrimination, MGH doctor talks about Social Distancing, Mask Control all by concordant MD Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 777 | 0 | 777 | 0 | 777 |
| EG005 | Ack. Discrimination- MGH - Mask (Control) - Discordant | Introduction Acknowledges past discrimination, MGH doctor talks about Social Distancing, Mask Control all by discordant MD Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 788 | 0 | 788 | 0 | 788 |
| EG006 | Ack. Econ. Circumstance- MGH - Mask (Control ) Concordant | Intro econ. circumstance -MGH - Mask (Control ) Concordant Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 783 | 0 | 783 | 0 | 783 |
| EG007 | Ack. Econ. Circumstance - MGH - Mask (Control ) Discordant | Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 788 | 0 | 788 | 0 | 788 |
| EG008 | Control Intro - CDC - Mask (antiStigma) Concordant | Control Intro - CDC - Mask (antiStigma) Concordant messenger Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 779 | 0 | 779 | 0 | 779 |
| EG009 | Control Intro - CDC - Mask (antiStigma) Discordant | Control Intro - CDC - Mask (antiStigma) discordant messenger Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 780 | 0 | 780 | 0 | 780 |
| EG010 | Control - MGH - MaskS (antiStigma) Concordant Messenger | Control - MGH - MaskS (antiStigma) Concordant sender Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 782 | 0 | 782 | 0 | 782 |
| EG011 | Control- MGH-MaskS (antiStigma) Discordant Messenger | Control - MGH - MaskS (antiStigma) Discordant sender Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 790 | 0 | 790 | 0 | 790 |
| EG012 | Ack. Discrimination - MGH - MaskS (antiStigma) Concordant | Acknowledge Discrimination - MGH - MaskS (antiStigma) Concordant sender Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 779 | 0 | 779 | 0 | 779 |
| EG013 | Ack. Discrimination - MGH - MaskS (antiStigma) Discordant | Acknowledge Discrimination - MGH - MaskS (antiStigma) Discordant sender Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 786 | 0 | 786 | 0 | 786 |
| EG014 | Ack. Econ Hardship- MGH - Mask (antiStigma) Concordant | Acknowledge Econ Hardship- MGH - Mask (antiStigma) Concordant sender Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 781 | 0 | 781 | 0 | 781 |
| EG015 | Ack. Econ Hardship- MGH - Mask (antiStigma) Discordant | Acknowledge Econ Hardship- MGH - Mask (antiStigma) discordant sender Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 781 | 0 | 781 | 0 | 781 |
| EG016 | Info Later - Pure Control | This group will not receive the videos but will receive information later. Messaging: o The video messages each participant in one of the treatment groups sees will be randomized on the following dimensions. The different versions are clearly demarcated in the US Doctors Scripts document.
| 0 | 1,617 | 0 | 1,617 | 0 | 1,617 |
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| D007239 |
| Infections |
| Female, age ≤44 y, coastal |
|
| Female, age ≤44 y, central |
|
| Male, age ≥45 y, coastal |
|
| Male, age ≥45 y, central |
|
| Male, age ≤44 y, coastal |
|
| Male, age ≤44 y, central |
|
| Argentina |
|
| Colombia |
|
| Ecuador |
|
| El Salvador |
|
| Guatemala |
|
| Nicaragua |
|
| Panama |
|
| Peru |
|
| Spain |
|
| Venezuela |
|
| Other country |
|
| Puerto Rico |
|