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The objective of the study is to develop and validate a molecular diagnostic strategy (RT-ddPCR multiplex) of COVID-19 based on a saliva sample and alternative to the RT-qPCR method, in order to :
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patient with COVID-19 infection suspicion | Experimental | Patient with COVID-19 infection suspicion are tested using standard diagnosis method |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Saliva collection | Diagnostic Test | Saliva collection will be done in addition to standard diagnosis collection (nasopharyngeal collection using swab) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of positive patient using saliva method compared to number of positive patient using standard method | One hour | |
| Number of negative patient using saliva method compared to number of negative patient using standard method | One hour |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Thierry FREBOURG, Pr | University Hospital, Rouen | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Rouen University Hospital | Rouen | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33331864 | Result | Cassinari K, Alessandri-Gradt E, Chambon P, Charbonnier F, Gracias S, Beaussire L, Alexandre K, Sarafan-Vasseur N, Houdayer C, Etienne M, Caron F, Plantier JC, Frebourg T. Assessment of Multiplex Digital Droplet RT-PCR as a Diagnostic Tool for SARS-CoV-2 Detection in Nasopharyngeal Swabs and Saliva Samples. Clin Chem. 2021 Apr 29;67(5):736-741. doi: 10.1093/clinchem/hvaa323. |
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