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| Name | Class |
|---|---|
| University of Oklahoma | OTHER |
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This study plans to learn more about how an omega-3 fatty acid supplement effects triglyceride levels in pregnancy. Triglycerides are a type of fat found in your blood. Your body converts extra calories into triglycerides to be stored and used later for energy. It is normal for triglyceride levels to go up during pregnancy however some women have levels that are ~30-40% higher than normal when they reach their third trimester of pregnancy. Having high triglycerides in pregnancy may be related to an increased chance of having a baby that is large for their age. The goal of this study is to determine if taking an omega-3 fatty acid supplement can slow the rise in triglyceride levels later in pregnancy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Omega 3 Supplementation | Experimental | Supplementation of 4g of DHA/EPA daily |
|
| Soybean oil | Placebo Comparator | Supplementation of 4g Soybean Oil |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Intervention Omega 3 Supplementation | Dietary Supplement | Participants will supplement 4g of Omega 3 fish oil daily (750DHA/250EPA) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Maternal Fasting and Postprandial Triglycerides | Differences in maternal fasting and postprandial triglycerides between groups | 34 weeks gestational age |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Teri L Hernandez, PhD | University of Colorado, Denver | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Colorado/Anschutz Medical Campus | Aurora | Colorado | 80045 | United States | ||
| University of Oklahoma Health Sciences Center |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 29931812 | Background | Barbour LA, Farabi SS, Friedman JE, Hirsch NM, Reece MS, Van Pelt RE, Hernandez TL. Postprandial Triglycerides Predict Newborn Fat More Strongly than Glucose in Women with Obesity in Early Pregnancy. Obesity (Silver Spring). 2018 Aug;26(8):1347-1356. doi: 10.1002/oby.22246. Epub 2018 Jun 22. |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| Placebo Soybean Oil | Dietary Supplement | Participants will supplement 4g of Soybean oil daily |
|
| Oklahoma City |
| Oklahoma |
| 73104 |
| United States |
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |