Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
This study examine the effect of Parasternal Intercostal Nerve Blocks with local anesthetic on pain control in patients undergoing non-emergent cardiac surgery in a prospective controlled trial. Half of participants will receive General Anesthesia combined to parasternal block while the other half receive only General Anesthesia.
60 patients undergoing elective cardiac surgery will be enrolled and divided into two groups:
The "case control group" will only receive drainage infiltration with local anesthetic and standard intraoperative management with opioids.
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Parasternal Group | Experimental | The "parasternal group" of patients will receive the pre-operative parasternal block (20 ml of 0.5% Ropivacaine per side) in association with infiltration with local anesthetic of access to thoracic drainage (drainage infiltration with 20 ml of 0.25% Ropivacaine) at the end of the intervention combined to General Anesthesia. |
|
| Case control group | Active Comparator | The "case control group" will only receive drainage infiltration with local anesthetic and standard intraoperative management with opioids. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Parasternal Block+ Infiltration with local anesthetic of access to thoracic drainage | Procedure | After induction of general anesthesia we will perform an ultrasound-guided Parasternal Block in association with infiltration with local anesthetic of access to thoracic drainage at the end of the intervention. |
| Measure | Description | Time Frame |
|---|---|---|
| Maximum Pain Score | Postoperative pain assessment using the NRS scale (score from 0 to 10) | 24 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Respiratory performance at the TRI-FLOW | Respiratory performance is assessed by the number of balls raised during inspiration with the TRI-FLOW | 24 hours |
| Intraoperative opioid administration | Quantitative evaluation of opioids needed in the intraoperative period |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Campus Biomedico University | Rome | Roma | 00128 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26827847 | Result | Chou R, Gordon DB, de Leon-Casasola OA, Rosenberg JM, Bickler S, Brennan T, Carter T, Cassidy CL, Chittenden EH, Degenhardt E, Griffith S, Manworren R, McCarberg B, Montgomery R, Murphy J, Perkal MF, Suresh S, Sluka K, Strassels S, Thirlby R, Viscusi E, Walco GA, Warner L, Weisman SJ, Wu CL. Management of Postoperative Pain: A Clinical Practice Guideline From the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' Committee on Regional Anesthesia, Executive Committee, and Administrative Council. J Pain. 2016 Feb;17(2):131-57. doi: 10.1016/j.jpain.2015.12.008. |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D000377 | Agnosia |
| D059787 | Acute Pain |
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D002318 | Cardiovascular Diseases |
| D010468 | Perceptual Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Infiltration with local anesthetic of access to thoracic drainage | Procedure | Infiltration with local anesthetic of access to thoracic drainage at the end of the intervention. |
|
| 4 hours |
| Total opioids consumption | Number of opioid deliveries (bolus morphine) in the postoperative period | 24 hours |
| Time to first opioid | The time in minutes between awakening and the first opioid administration | 48 hours |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |