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Patients experiencing pain after undergoing cardiac surgery may also experience prolonged immobilization, insufficient respiratory functions, and the inability to cough due to median sternotomy. Therefore, duration of mechanical ventilation, length of intensive care unit (ICU) stay, and length of hospital stay of these patients will increase significantly.
many facial plane blocks have been introduced as simple and safe intervention for thoracic wall anesthesia and analgesia. Parasternal intercostal nerve block (PSIB) is a "superficial block" which involves local anesthetic (LA) infiltration in the intercostal space around the sternum where the anterior branches of intercostal nerves exist.
Intraoperative LA administration under direct vision of the surgeon ensures adequate delivery of drugs and minimizes bleeding complication or inadvertent administration in blood vessels. Meanwhile, Preoperative administration of LA guided by ultrasound imaging has been used in variable surgical settings with noticeable success because of preemptive inhibition of noxious stimuli.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pre-incisional parasternal block | Active Comparator | ultrasound guided parasternal intercostal block will be administrated before surgical incision. |
|
| Post-incisional parasternal block | Active Comparator | under direct vision parasternal intercostal block will be administrated after surgical incision and before closure of the sternum. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| pre-incisional parasternal intercostal block | Procedure | LA will be administrated by the anesthesiologist under ultrasound guidance and before surgical incision On either side of thorax, 2 cm lateral to sternal edge from 2nd to 6th intercostal space, A volume of (4 mL) of 0.25% bupivacaine will be used |
| Measure | Description | Time Frame |
|---|---|---|
| Amount of rescue analgesia | Total amount of opioid administered as rescue analgesia postoperative. | 24 hours postoperative |
| Measure | Description | Time Frame |
|---|---|---|
| Intraoperative total fentanyl requirements | the amount of consumed opioid during the procedure | during surgery |
| intraoperative mean arterial blood pressure (MAP) | hemodynamic variability due to surgical stimulation |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Samar Rafik Amin | Banhā | Qalyubia Governorate | 13511 | Egypt |
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| ID | Term |
|---|---|
| D059787 | Acute Pain |
| ID | Term |
|---|---|
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
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|
| post-incisional parasternal intercostal block | Procedure | LA will be administered by the cardiac surgeon before the sternal closure. injection will introduced 2 cm lateral to sternal edge from 2nd to 6th intercostal space and volume (4 mL) of 0.25% bupivacaine will be used. |
|
| during surgery (baseline, at skin incision, at sternotomy, at sternal retraction) |
| pain score (VAS) | VAS scores will be recorded by making a handwritten mark on a 10-cm line that represented a continuum between "no pain" and "worst possible pain." | at extubation, 12th, 16th, 20th, and 24th hour postoperative |
| adverse effects | nausea, vomiting, excessive sedation, respiratory depression | 24 hours postoperative |
| patient satisfaction | 0 "extremely unsatisfied" to 10 "extremely satisfied" | 28 hours postoperative |
| Intensive Care Unit (ICU) Length of Stay | up to 6 months |