Predictors of Respiratory Failure in SARS-Cov-2 Infection

Predictors of Respiratory Failure Requiring ICU Admission Among Hospitalized Patients With SARS-Cov-2 Infection

The emergence of SARS-CoV-2 is currently engaging and consuming most of resources of efficient healthcare systems in Europe, and several hospitals are currently experiencing a shortage of ICU beds for critically-ill patients with SARS-CoV-2 pneumonia.

A risk stratification based on clinical, radiological and laboratory parameters seems necessary in order to better identify those patients who may need ICU admission and/or those who may benefit from a prompt antiviral therapy

The study will compared patients with and without respiratory failure in order to find risk factors for need for ICU admission. A simple score based on risk factors will be created from a multicenter Italian cohort and validated in a multicenter international cohort.

Inclusion Criteria:

• Hospitalized patients with microbiologically confirmed diagnosis of SARS-CoV-2 infection
• Age > 17 years

Exclusion Criteria:

• Invasive mechanical ventilation within 12 hours from hospital admission