Neurobehavioral Mechanisms of Cocaine Choice

Neurobehavioral Mechanisms of Cocaine Choice

The objective of this protocol is to use a drug-vs-money choice task, reinforcement learning modeling and fMRI to determine the neurobehavioral and neurobiological decision-making "profile" associated with the decision to take cocaine and the reduced cocaine choice that occurs during a behavioral intervention (alternative money reinforcer) that models contingency management.

Inclusion Criteria:

• Recent cocaine use, otherwise healthy

Exclusion Criteria:

• Laboratory results outside of clinically acceptable ranges, history of or current serious physical or psychiatric disease