Impact of a Non-Drug Choice on Cocaine Reinforcement

Impact of a Non-Drug Choice on Cocaine Reinforcement

Cocaine-use disorders continue to be a significant public health concern, yet no effective medications have been identified. The goal of this study is to establish a research platform for the development of medications for treatment of cocaine abuse and dependence. This study will incorporate self-administration procedures and a non-drug alternative reinforcer, which is hypothesized to reduce the reinforcing effects of cocaine.

Inclusion Criteria:

• Cocaine dependence, otherwise healthy

Exclusion Criteria:

• Laboratory results outside of clinically acceptable ranges, history of or current serious physical or psychiatric disease