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| ID | Type | Description | Link |
|---|---|---|---|
| 2019-A01395-52 | Other Identifier | ANSM, France |
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Data from the literature on the management of Chronic Coronary Occlusions (CTO) in France highlight a lack of epidemiological data on these patients at the national level.
For this reason, it was decided to set up this large-scale survey in order to have a picture of the management of patients with chronic coronary occlusion in France, to study the prevalence of CTOs in France as well as their management (medical, surgical or interventional), and then by analysing more precisely, over a second survey period, CTO angioplasties in terms of success rates, complications, medico-economic impact.
This exhaustive and descriptive study of CTO patients, performed on a set of approximately 100 interventional cardiology centers in France, will be conducted in two steps:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CTO | Period of 1 month in the participating centers, during which all the patients with CTO and responding to all selection criteria may be included in the study, in order to describe which therapeutic choices have been chosen for this type of patient. | ||
| CTO with attempted angioplasty | Period of 2 months in the participating centers, during which all the patients for whom an angioplasty has been attempted after a CTO, and responding to all selection criteria, may be included in the study, in order to evaluate the success of the procedure |
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| Measure | Description | Time Frame |
|---|---|---|
| Choice of treatment in management of patients with CTO | Rate of patients with CTO treated by medical treatment alone and/or by surgery, and/or by angioplasty | Through the end of hospitalization, an average of 5 days |
| Success of the angioplasty for management of CTO | Procedural success rate defined by residual stenosis ≤ 30% with a TIMI (Thrombolysis In Myocardial Infarction) 3 flow and no hospital complications at the end of the angioplasty procedure | Through the end of hospitalization, an average of 5 days |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of events occured after procedure of angioplasty during the hospitalization, for patients with CTO | Major Adverse Cardiac and Cerebrovascular Events (MACCE - defined as the composite of death, Myocardial Infarction (MI), CerebroVascular Accident (CVA) or Stroke, or Target Vessel Revascularisation (TVR)) | Through the end of hospitalization, an average of 5 days |
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Phase I
Inclusion Criteria:
Exclusion Criteria:
Phase II
Inclusion Criteria:
Exclusion Criteria:
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As defined by the European CTO Club consensus, a chronic occlusion (CTO) is a total coronary occlusion, TIMI 0 (without anterograde coronary flow), more than 3 months old.
To assess the CTO, the JCTO score will be used to assess the clinical and angiographic criteria of the lesions.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinique Saint Augustin | Bordeaux | 33075 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 19737682 | Background | Di Mario C, Werner GS, Sianos G, Galassi AR, Buttner J, Dudek D, Chevalier B, Lefevre T, Schofer J, Koolen J, Sievert H, Reimers B, Fajadet J, Colombo A, Gershlick A, Serruys PW, Reifart N. European perspective in the recanalisation of Chronic Total Occlusions (CTO): consensus document from the EuroCTO Club. EuroIntervention. 2007 May;3(1):30-43. No abstract available. | |
| 8362709 |
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| ID | Term |
|---|---|
| D054059 | Coronary Occlusion |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| Background |
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| D014652 |
| Vascular Diseases |