Effect of CI on Prognosis in the Elderly Patients With ACS

Effect of Cognitive Impairment (CI) on Prognosis in the Elderly Patients With Acute Coronary Syndrome (ACS)

This study aims to investigate the incidence and characteristics of cognitive Impairment(CI) in the elderly patients with acute coronary syndrome (ACS), and to determine whether CI are predictive of the prognosis of major adverse cardiovascular events (MACE) and mortality.

Inclusion Criteria:

• ≥65yr
• Confirmed ACS diagnosis （include unstable angina, ST-segment elevation myocardial infarction and Non ST-segment elevation myocardial infarction）
• fulfilled MMSE or MoCA
• patients agreed and provided informed consent

Exclusion Criteria:

• Type 2 myocardial infarction and Acute nonischemic myocardial injury
• past history of malignant tumors
• Past history of stroke or dementia
• Hepatic insufficiency (ALT>8ULN or ALT>3ULN and TBIL>2ULN)
• Renal insufficiency (GFR<15 ml/min/1.73m2)