The Cognitive and Cardiovascular Health in the Elderly Study

The Cognitive and Cardiovascular Health in the Elderly Study

The main objective of this study is to look for the interest forecast of the IPS as infra-clinical cardiovascular marker in the prediction of a change of the cognitive functions (MCI) at the elderly of 70 and more years old without clinical cardiovascular pathology.

Inclusion Criteria:

• free-living community-dwelling men and women aged ≥ 70 years,
• subjects free of clinical CVD related to atherosclerosis
• preserved basic activities of daily living (ADL = 6)
• without cognitive impairment (MMSE≥24)

Exclusion Criteria:

• subjects with clinical history of any of the following CVD diseases : coronary artery disease (angina, myocardial infarction, coronary revascularization), cerebrovascular disease (stroke, TIA, carotid revascularization), clinical peripheral artery disease (claudication, critical limb ischemia)
• subjects with neurodegenerative, locomotor and ophtalmological diseases unable to perform the cognitive tests
• subjects unable to give written informed consent.