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| Name | Class |
|---|---|
| People's Hospital of Guangxi Zhuang Autonomous Region | OTHER |
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Compare postoperative Subjective and objective visual quality and economic efficiency of different Intraocular Lens(IOLs) implantation designed for the correction of presbyopia.
Compare postoperative Subjective and objective visual quality and economic efficiency of different Intraocular Lens Implantation designed for the correction of presbyopia.The subjects will undergo bilateral uneventful phacoemulsification and implantation of IOL.The subjects will be divided into several groups according to the type of the IOLs，including monofocal IOL group,monovision designed group ，bifocal IOL group, mix bifocal IOL group，trifocal IOL group，Exteded Depth of Focus(EDOF) IOL group and blend vision group. Compare the Subjective and objective visual quality and economic efficiency among these groups at 3 months postoperatively.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| bifocal IOL group | The cataract patients who ask for bilateral phacoemulsification and bifocal IOLs implantation. |
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| mix bifocal IOL group | The cataract patients who ask for phacoemulsification and mix different bifocal IOLs implantation bilaterally |
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| trifocal IOL group | The cataract patients who ask for bilateral phacoemulsification and trifocal IOLs implantation. |
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| EDOF IOL group | The cataract patients who ask for bilateral phacoemulsification and EDOF IOLs implantation. |
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| blend vision group | The cataract patients who ask for phacoemulsification and different IOLs implantation bilaterally. |
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| monovision designed group | The cataract patients who ask for bilateral phacoemulsification and monofocal IOLs implantation with monovision designed. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| bifocal IOL | Device | The patients will undergo bilateral phacoemulsification and bifocal IOLs implantation. |
|
| Measure | Description | Time Frame |
|---|---|---|
| monocular and binocular visual acuity | uncorrected distance visual acuity (UCVA), intermediate visual acuity, near visual acuity will be measured at 5m, 80cm and 40cm respectively. All visual acuity measurements will be conducted under photopic conditions (85 cd/m2) and at 100% contrast | 3 months postoperatively |
| economic efficiency | economic efficiency was defined as the ratio of objective spectacle independence (UCVA better than 0.10 logMAR) and IOL price, then compare the economic efficiency among different groups. | 3 months postoperatively |
| Measure | Description | Time Frame |
|---|---|---|
| Binocular Contrast sensitivity | Contrast sensitivity measures will be conducted binocularly, under photopic, mesopic (5 cd/m2), photopic with glare and mesopic with glare conditions, with the OPTEC 6500 contrast sensitivity test (Stereo Optical, USA). Contrast sensitivity will be evaluated at five spatial frequencies (1.5, 3, 6, 12, and 18 cycles per degree [cpd]). Patients will be allowed 5 minutes to adapt to each illumination level before testing. |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with bilateral cataract
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Qianqian Lan | Contact | +8618607711972 | 54283122@qq.com |
| Name | Affiliation | Role |
|---|---|---|
| Qi Hong, PhD，MD | Peking University Third Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking University Third Hospital | Recruiting | Beijing | Beijing Municipality | 100191 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 40389895 | Derived | Sun T, Zhao X, Liu Y, Lan Q, Tang C, Qin R, Bian L, Li W, Qi H. Neurosensory binocular vision after bilateral implantation of an extended depth of focus intraocular lens with micro-monovision: a prospective cohort study. BMC Ophthalmol. 2025 May 19;25(1):294. doi: 10.1186/s12886-025-04125-5. | |
| 36266642 | Derived |
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| monofocal IOL group | The cataract patients who ask for bilateral phacoemulsification and monofocal IOLs implantation with emmetropia designed. |
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| mix bifocal IOL | Device | The patients will undergo phacoemulsification and mix different bifocal IOLs implantation bilaterally. |
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| trifocal IOL | Device | The patients will undergo bilateral phacoemulsification and trifocal IOLs implantation. |
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| EDOF IOL | Device | The patients will undergo bilateral phacoemulsification and EDOF IOLs implantation. |
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| different IOLs | Device | The patients will undergo phacoemulsification and different IOLs implantation bilaterally. |
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| monofocal IOL | Device | The patients will undergo bilateral phacoemulsification and monofocal IOLs implantation with monovision designed. |
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| monofocal IOL | Device | The patients will undergo bilateral phacoemulsification and monofocal IOLs implantation with emmetropia designed. |
|
| 3 months postoperatively |
| Binocular Defocus Curve | Binocular defocus curves will be obtained in all patients, positioned at 5m under photopic (>85 cd/m 2 ) condition to measure the visual acuity with each defocus lens, representing the consecutive visual function of each eye. Negative lenses were added in 0.50 D steps and the visual acuity will be recorded for each type of defocus level. The procedure will be then repeated but with positive lenses. The range of defocus evaluated is from -4.00D to +2.00D. | 3 months postoperatively |
| stereopsis | distant stereopsis will be measured by block diagram of random-spot synoptophore, while near stereopsis will be measured by Yan's stereogram. | 3 months postoperatively |
| Fusion function | The fusion function of perception and movement (convergence and divergence)will be examined with a synoptophore. | 3 months postoperatively |
| Subjective visual quality | Using NEI-VFQ-25 questionnaire (Chinese version). Photic phenomena, spectacle independence, and satisfaction questionnaire. | 3 months postoperatively |
| Sun T, Liu Y, Gao Y, Tang C, Lan Q, Yang T, Zhao X, Qi H. Comparison of visual outcomes of a diffractive trifocal intraocular lens and a refractive bifocal intraocular lens in eyes with axial myopia: a prospective cohort study. BMC Ophthalmol. 2022 Oct 20;22(1):407. doi: 10.1186/s12886-022-02626-1. |
| 36071311 | Derived | Lan Q, Liu Y, Xu F, Li M, Li Y, Yang T, Sun T, Yao G, Ma B, Tao L, Xiao X, Feng XL, Zeng S, Qi H. Cost-Effectiveness of Presbyopia Correction Among Seven Strategies of Bilateral Cataract Surgery Based on a Prospective Single-Blind Two-Center Trial in China. Ophthalmol Ther. 2022 Dec;11(6):2067-2082. doi: 10.1007/s40123-022-00562-3. Epub 2022 Sep 7. |
| ID | Term |
|---|---|
| D011305 | Presbyopia |
| ID | Term |
|---|---|
| D012030 | Refractive Errors |
| D005128 | Eye Diseases |
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