Adipose Inflammation and Diabetes (FAB)

Adipose Tissue Inflammation and Diabetes Development (Fettvävsinflammation Och Diabetesutveckling)

The study investigates whether the addition of resolution molecules can inhibit inflammation and insulin resistance in human tissue taken from obese individuals, and whether the results of these studies correlate with patient-specific resolution phenotypes.

Inclusion Criteria:

• BMI 30-40 kg/m2
• Ptos (i.e. excess skin) > 3 cm
• Patient underwent gastric bypass surgery >2 years ago
• Patient has had a stable weight ≥6 months at the time of operation
• Patient does not smoke (min 6 weeks prior to surgery)

Exclusion Criteria:

• Patients who do not understand spoken and written Swedish
• American Society of Anesthesiologists (ASA) classification ≥ 3
• Neurological, orthopedic or rheumatologic injury or illness affecting physical ability
• Preoperatively known hernia requiring surgical operation
• Severe mental illness