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The study investigates whether the addition of resolution molecules can inhibit inflammation and insulin resistance in human tissue taken from obese individuals, and whether the results of these studies correlate with patient-specific resolution phenotypes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Study patients | Obese subjects scheduled to undergo abdominoplasty surgery are included. These are later classified according to metabolic status. |
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| Measure | Description | Time Frame |
|---|---|---|
| Inflammatory status | The inflammatory status will be studied in obese patients. | 2025 |
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Inclusion Criteria:
Exclusion Criteria:
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The patients participating in this study must have undergone a gastric bypass surgery >2 years ago, and currently have excess skin of > 3 cm, thus requiring an abdominoplasty surgery. We only include patients that are obese (BMI 30-40 kg/m2). Patients interested in participating in the study donate the skin and adipose tissue that is discarded during surgery. In addition, they donate blood samples prior to surgery.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Emma Borgeson, PhD | Contact | +46313420000 | emma.borgeson@wlab.gu.se | |
| Christina Biörserud, RN, PhD | Contact | +46313420000 | christina.biorserud@vgregion.se |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sahlgrenska university hospital | Recruiting | Gothenburg | Västra Götaland County | 40530 | Sweden |
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| ID | Term |
|---|---|
| D009765 | Obesity |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
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| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |