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| Name | Class |
|---|---|
| Noho Health | UNKNOWN |
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A 90 day eight arm virtual interventional study looking at the impact of various supplement formulations for improves in hair, skin & nail health via self report, and dermatology assessment via remote dermatologist assessment.
This study is being run entirely on the ProofPilot clinical trial platform. Participants enroll online, submit selfies, and are shipped dietary various dietary supplements containing a one or more of Keratin, Astaxanthin, Collagen Peptides and Pro-berry powder in vegan and non-vegan formats. All participants will receive active ingredients but in various fomulations.
Half the participants will receive the formations for free. The other half will pay a discounted amount for the supplements.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Veg Collagen & Keratin Free (Hair Skin Nails) | Experimental | Participants will receive a free 3 month supply of Collagen & Keratin for Hair, Skin & Nail Health |
|
| Veg Collagen Extended with Powder Free (Hair Skin Nails) | Experimental | Participants will receive a free 3- month supply of Collagen & Keratin for Hair, Skin & Nail Health extended with a pro-berry powder |
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| Veg Collagen & Keratin $$$ (Hair Skin Nails) | Experimental | Participants will receive a paid 3-month supply of Collagen & Keratin for Hair, Skin & Nail Health |
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| Veg Collagen Extended with Powder $$$ (Hair Skin Nails) | Experimental | Participants will receive a paid 3-month supply of Collagen & Keratin extended with pro-berry powder for Hair, Skin & Nail Health |
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| Ceramides and Astaxanthin Free (Skin) | Experimental |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Vegetarian Collagen | Dietary Supplement | Collagen is a protein made up of amino-acids, which are in turn built of carbon, oxygen and hydrogen. |
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| Measure | Description | Time Frame |
|---|---|---|
| Changes in Self-Report Skin, Hair & Nail Health and Satisfaction | A custom self-report survey for participants to self-assess their satisfaction on skin, hair and nail status. | Baseline, 30 Day, 60 Day and 90Day |
| Blinded Dermatology Assessment of Facial Skin health | Comparison over timepoints of physician assessment of facial features at rest and smile to the Glogau & customer wrinkle selfie scale | Baseline 45 day and 90 day |
| Participant Acceptability | Week by week change and overall analysis of custom survey delivered weekly asking participants to self report acceptability and adherence to treatment regiment over prior week. | weekly |
| Paid versus unpaid particpatnt adherence | Comparison of arms with the same intervention, but one paid, one not, to assess impact on adherence | 30 and 90 Day |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| ProofPilot Online App (https://p.proofpilot.com) | New York | New York | 10003 | United States |
There are currently no plans to make participant data available to other participants.
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| ID | Term |
|---|---|
| D000505 | Alopecia |
| D003483 | Cutis Laxa |
| ID | Term |
|---|---|
| D007039 | Hypotrichosis |
| D006201 | Hair Diseases |
| D012871 | Skin Diseases |
| D017437 | Skin and Connective Tissue Diseases |
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| ID | Term |
|---|---|
| D007633 | Keratins |
| D002518 | Ceramides |
| C005948 | astaxanthine |
| ID | Term |
|---|---|
| D007381 | Intermediate Filament Proteins |
| D001704 | Biopolymers |
| D011108 | Polymers |
| D046911 | Macromolecular Substances |
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Participants are randomized into one of eight arms. The arms include four combinations of dietary supplements for skin, hair & nail health (Keratin, collagen peptides, pro-berry powder, vegan Keratin, and Astaxanthin). Each supplement formation is included in two arms - one arm is paid, the other arm is free.
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This study is done completely online. Supplements are fulfilled at a central fulfillment center. The study sponsor, nor any care provider, or investigator know what formulation a participant receives until the end of the study
Participants will receive a free 3-month supply of ceramides and Astaxanthin for Hair, Skin & Nail Health
|
| Ceramides and Astaxanthin Extended with Powder Free (Skin) | Experimental | Participants will receive a free 3-month supply of Ceramides and Astaxanthin for Hair, Skin & Nail Health |
|
| Ceramides and Astaxanthin $$$ (Skin) | Experimental | Participants will receive a paid 3-month supply of Ceramides and Astaxanthin extended with pro-berry powder for Hair, Skin & Nail Health |
|
| Ceramides and Astaxanthin Extended with Powder $$$ (Skin) | Experimental | Participants will receive a paid 3-month supply of Ceramides and Astaxanthin extended with pro-berry powder for Hair, Skin & Nail Health |
|
| Keratin | Dietary Supplement | Keratin (/ˈkɛrətɪn/) is one of a family of fibrous structural proteins known as scleroproteins. α-Keratin is a type of keratin found in vertebrates. It is the key structural material making up hair, nails, feathers, horns, claws, hooves, calluses, and the outer layer of skin among vertebrates. |
|
| Ceramides | Dietary Supplement | Ceramides are a family of waxy lipid molecules. A ceramide is composed of sphingosine and a fatty acid. Ceramides are found in high concentrations within the cell membrane of eukaryotic cells, since they are component lipids that make up sphingomyelin, one of the major lipids in the lipid bilayer. |
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| Astaxanthin | Dietary Supplement | is a naturally-occurring carotenoid found in algae, shrimp, lobster, crab and salmon. |
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| D020763 |
| Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D012873 | Skin Diseases, Genetic |
| D030342 | Genetic Diseases, Inborn |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D003240 | Connective Tissue Diseases |
| D003598 |
| Cytoskeletal Proteins |
| D011506 | Proteins |
| D000602 | Amino Acids, Peptides, and Proteins |
| D012596 | Scleroproteins |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D020383 | Neutral Glycosphingolipids |
| D006028 | Glycosphingolipids |
| D006017 | Glycolipids |
| D006001 | Glycoconjugates |
| D002241 | Carbohydrates |
| D008055 | Lipids |
| D013107 | Sphingolipids |
| D008563 | Membrane Lipids |