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In the present study, we observe perioperative findings of electroencephalogram in sedated and non-sedated elderly patients undergoing total knee arthroplasty under spinal anesthesia.
In the present study, we observe perioperative findings of electroencephalogram in sedated and non-sedated elderly patients undergoing total knee arthroplasty under spinal anesthesia. Electroencephalogram is performed before, during, and 1 day after surgery.
After the induction of anesthesia, sedation is performed according to the patient's request. If a patient want to be sedated during surgery, one of the three sedatives (dexmedetomidine, propofol, and midazolam) is administered.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control | Patients who do not want to be sedated during spinal anesthesia are included. Electroencephalogram is performed before, during, and 1 day after surgery. |
| |
| Dexmedetomidine | Patients who want to be sedated during spinal anesthesia are included. Electroencephalogram is performed before, during, and 1 day after surgery. After the induction of spinal anestheisa, dexmedetomidine is administered for sedation during surgery. |
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| Propofol | Patients who want to be sedated during spinal anesthesia are included. Electroencephalogram is performed before, during, and 1 day after surgery. After the induction of spinal anestheisa, propofol is administered for sedation during surgery. |
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| Midazolam | Patients who want to be sedated during spinal anesthesia are included. Electroencephalogram is performed before, during, and 1 day after surgery. After the induction of spinal anestheisa, midazolam is administered for sedation during surgery. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Electroencephalogram | Device | Electroencephalogram is performed before, during, and 1 day after surgery in elderly patients undergoing spinal anesthesia. |
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| Measure | Description | Time Frame |
|---|---|---|
| EEG frequency bands (alpha, beta, theta, delta, and gamma waves) during spinal anesthesia | EEG frequency bands are observed during spinal anesthesia under sedated or unsedated states. | 30 min after the induction of spinal anesthesia |
| Measure | Description | Time Frame |
|---|---|---|
| EEG frequency bands (alpha, beta, theta, delta, and gamma waves) 1 day after surgery | EEG frequency bands are observed after surgery and compared with the preoperative findings. | 1 day after surgery |
| Incidence of delirium |
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Inclusion Criteria:
Exclusion Criteria:
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Elderly patients scheduled to undergo total knee arthroplasty under spinal anesthesia
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| ID | Term |
|---|---|
| D004569 | Electroencephalography |
| ID | Term |
|---|---|
| D003943 | Diagnostic Techniques, Neurological |
| D019937 | Diagnostic Techniques and Procedures |
| D003933 | Diagnosis |
| D004568 | Electrodiagnosis |
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Delirium is assessed after surgery.
| For 7 days after surgery. |