Comparison of Different PEEP Titration Strategies Using Electrical Impedance Tomography in Patients With ARDS

Comparison of Different Positive End-expiratory Pressure Titration Strategies Using ELectrical Impedance Tomography in Patients With Acute Respiratory Distress Syndrome : the DELTA Physiological Study

The aim of the this study is to assess the short term physiological effects of 3 ventilation strategies for adult patients with ARDS admitted to intensive care unit.

Two of those strategies are based on electrical impedance tomography (EIT) monitoring.

Inclusion Criteria:

• patients with moderate to severe ARDS, defined by the Berlin consensus, at 12 to 48h from diagnosis
• PaO2/FiO2 ratio < 150 mmHg
• Patient affiliated to or beneficiary of a health care plan
• Consent obtained from patient's SDM

Exclusion Criteria:

• Pneumothorax
• Contraindication to the insertion of a nasogastric tube with an esophageal balloon
• Contraindication to the use of Electrical impedance tomography
• Pregnancy, lactating or parturient woman